Estrogen Up-regulates Androgen Receptors (AR) In The Brain

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TheBeard

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Estrogen generally potentiates testosterone's activity at the androgen receptor, not only in the brain
 

LeeLemonoil

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How much estrogen is needed for this to happen though?

That’s the important matter. It’s a homeostatic response. There is a too much and a top little and both states depend on the situation of the tissue and what is „beneficial“ there at any given moment.
 

LeeLemonoil

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Up- and downregulation of receptors and „sensitivity“ to ligands are a freakish matter.
 

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