Estrogen, Not Androgens, May Be The Cause Of Baldness

LUH 3417

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I think it might be liver related in most bb's? Taking high amounts of down stream steriods is never going to end well and T seems to be abused. They also tend to abuse AI's which are super hard on the liver. I have a friend who is 'juiced'. His eyes always have a reddish tinge to them.

Preg, prog and dhea seem to have had the opposite effect on my own eyes. They are clear, white and shiny. I take this as a sign of liver health improvement. Its either the catatoxic effect of these steroids or their effect of endotoxin I think.
I find my eyes are reddish when I take t3. Do you have any idea why?
 

JKX

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When I first tried aspirin the same thing happened. My liver wasnt in great shape at that point and I think sugar wasnt being used efficiently so I was getting mild acidosis symptoms. After about 2months or so of use my eyes became shiny and clear. This was long before I tried preg, prog or dhea.

If you havent read danny roddys article on the liver I'd highly recommend it:
The Danny Roddy Weblog

The acidosis is likley to improve in a month or 2 as health improves. A little sodium acetate, Taurine or glycine may help your livers ability to store sugar. B vitamins especially b1, b2, b3, b6 and b7 are important. As are zinc and magnesium. Making sure your getting enough calcium is a given.
 

mrchibbs

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If you havent read danny roddys article on the liver I'd highly recommend it:
The Danny Roddy Weblog

I find the older Danny Roddy articles to be terribly underrated. The guy writes beautifully, and gets across ideas in a simple and direct manner, while referencing the literature properly. He's very humble, but everytime I re-read one of his articles or even Hair like a Fox (Danny has come a long way since 2013), I still come away very impressed.

He's like the best hair loss researcher over the past decade, and I don't think he gets credit where credit is due.
 

LUH 3417

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Oct 22, 2016
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When I first tried aspirin the same thing happened. My liver wasnt in great shape at that point and I think sugar wasnt being used efficiently so I was getting mild acidosis symptoms. After about 2months or so of use my eyes became shiny and clear. This was long before I tried preg, prog or dhea.

If you havent read danny roddys article on the liver I'd highly recommend it:
The Danny Roddy Weblog

The acidosis is likley to improve in a month or 2 as health improves. A little sodium acetate, Taurine or glycine may help your livers ability to store sugar. B vitamins especially b1, b2, b3, b6 and b7 are important. As are zinc and magnesium. Making sure your getting enough calcium is a given.
Thanks, I take B complex and drink magnesium water, also took an aspirin today, but I’ve been drinking more alcohol than usual and diet has been not the best so maybe I’m dealing with some other issues.
 

mrchibbs

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Aromasin wrecked my hair.

Georgi talked about this in a recent podcast. Aromatase inhibitors aren't purely selective to estrogen, they affect many other hormones as well.

In this case Exemestane (Aromasin) also does possibly the worse thing you can think of: it blocks the conversion of cholesterol to pregnenolone

upload_2020-6-21_11-34-53.png


No wonder you hair took a hit.
 
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A quick post about a study calling into question yet another dogma in medicine - i.e. that the "evil" androgens (especially DHT) are the causes of men losing their hair and getting prostate cancer. So, the "solution" modern medicine proposes is "chemical castration" with drugs like finasteride, dutasteride, flutamide, bicalutamide, etc that render men impotent, demented, and overall very far from being...men, let alone healthy ones. I have studies in the works attempting to debunk one of those myths - DHT as a cause of prostate cancer - but the study below is already pointing at another part of the myth about DHT being false. It demonstrates that estrogen, and not androgens, cause hair loss in males and administration of estrogen "receptor" antagonists restores hair back to normal levels. The estrogen receptor antagonist used in the studies below was the breast-cancer drug Fulvestrant (ICI-182780) and just twice weekly topical application was enough to restore hair growth to control levels. After 12 weeks of treatment ALL bald mice had hair-growth restored to control levels. Progesterone is the main endogenous estrogen antagonist and works similarly to Fulvestrant. Other estrogen antagonists such as (gasp!) DHT and even aromatase inhibitors such as exemestane may also work. What about the dose? Well, the study used 10 nMol Fulvestrant dissolved in 200uL of acetone, and applied that dosage topically, only twice weekly, to treat an area of 10 cm^2. Since progesterone has roughly the same affinity/antagonism for the estrogen receptor as Fulvestrant, the HED of progesterone to replicate the design of this study would be about 10mcg/kg bodyweight for every 10 cm^2 of balding area. This means a man weighing 100kg would need to apply roughly 1mg of progesterone for every 10 cm^2 of balding area. Applying even higher amount or more often, if there is no response within 3-4 weeks, should be fine as progesterone is not known to inhibit hair growth even in massive doses. As a side note, if androgenic antagonists of the estrogen receptor (e.g. DHT, Masteron, exemestane, etc) are used then just to stay on the safe side, I would not use more than 1mg for every 10 cm^2, and would stick to the twice weekly regimen.

Perhaps the most promising finding of the research is not so much about possible hair-loss treatments but the connection between estrogen and skin cancer. In fact, the lead author of the studies below stated that the same estrogen blocker used to restore growth may also be useful as skin cancer treatment/prevention. Oh well, it seems medicine is not entirely a lost cause and is slowly getting back on the right track :):

https://repository.lib.ncsu.edu/handle/1840.16/5314
https://core.ac.uk/download/pdf/82416775.pdf
HAIR-RAISING TEST - ESTROGEN LINKED TO BALDNESS

"...Dr. Robert Smart and graduate assistant Hye-Sun Oh were studying the pesticide's impact when they found that the shaved skin of mice grew hair when treated with an estrogen blocker."Estrogen was playing some fundamental role in skin biology," Smart said. The discovery by the North Carolina State University researchers was published in Tuesday's edition of the Proceedings of the National Academy of Sciences. The discovery is being tested for possible application in humans, but any commercial use could be five years away, Smart said. Smart said the studies also provided insights into skin cancer, but a scientist who wasn't involved in the research said it was too soon to suggest the data may lead to cures for either condition....Smart said the estrogen blocker acts as a switch to turn on hair growth in the lab mice. He said research to determine if the same switch exists in humans is underway at Wake Forest University's Bowman-Gray School of Medicine."

Baldness gets thin explanation Hair: Researchers agree on how hair grows but have yet to discover the definitive reason for male-patterned baldness.

"..."...The latest debate erupted last year when Dr. Robert Smart, a researcher at North Carolina State University, reported that the female hormone estrogen harmed hair follicle growth, and hence played a role in baldness. Published in the Proceedings of the National Academy of Sciences, Smart's research entailed clipping off the hair of three groups of mice. One group then was coated with a chemical that arrested hair growth for a prolonged period. Two control groups received chemicals that had a minimal effect. When Smart treated the denuded skin of the first group with an estrogen-blocking drug, their hair follicles responded. Within 10 weeks, the mice produced coats so thick they were indistinguishable from untreated mice. Smart says the estrogen blocker prevented normal estrogen stimulation and hair growth was the result."
Good to know, my hair was thining and shedding a lot that i had to shave my head to cover my baldness. Since i started my regimen cortinon, 11 keto dht, pregnenolone, calcirol, kuinone and tyromixmy hair has been restored almost completely. I was thinking about hair transplant but now i dont think it will be necessary. Thanks Haidut for such great products.
 

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mrchibbs

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Good to know, my hair was thining and shedding a lot that i had to shave my head to cover my baldness. Since i started my regimen cortinon, 11 keto dht, pregnenolone, calcirol, kuinone and tyromixmy hair has been restored almost completely. I was thinking about hair transplant but now i dont think it will be necessary. Thanks Haidut for such great products.

Congrats. Never think about a transplant again lol!

You look younger and much healthier as well!

And you look like you have a really lovely little girl and a nice beach. You're living the good life!
 

Blue09

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Good to know, my hair was thining and shedding a lot that i had to shave my head to cover my baldness. Since i started my regimen cortinon, 11 keto dht, pregnenolone, calcirol, kuinone and tyromixmy hair has been restored almost completely. I was thinking about hair transplant but now i dont think it will be necessary. Thanks Haidut for such great products.

Hey man your hair looks great. May I ask how long it took to get some regrowth? That's a lot of supplements your taking do you get any side effects?
 
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Hey man your hair looks great. May I ask how long it took to get some regrowth? That's a lot of supplements your taking do you get any side effects?

No side effects, 3 drops cortinon, 2 drops pregnenolone, 2 drops calcirol in the mornings. Then 2 drops pregnenolone, 2 drops calcirol in the afternoons. 11 keto dht 5 drops every other day. Tyromix 2 drops after a heavy cholesterol meal. But you know what is the wonder? I used to be lactose intolerant and i cant tell you wich supplement fixed the problem but now a can drink a gallon of milk without worrying about diarrhea. You need to try what works for you through trial and error.
 

Blue09

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No side effects, 3 drops cortinon, 2 drops pregnenolone, 2 drops calcirol in the mornings. Then 2 drops pregnenolone, 2 drops calcirol in the afternoons. 11 keto dht 5 drops every other day. Tyromix 2 drops after a heavy cholesterol meal. But you know what is the wonder? I used to be lactose intolerant and i cant tell you wich supplement fixed the problem but now a can drink a gallon of milk without worrying about diarrhea. You need to try what works for you through trial and error.


Would you say its a combination of all of those supplements that helped your hair or perhaps just one or two. I'd like to try all of them but that would be quite expensive.
 
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Would you say its a combination of all of those supplements that helped your hair or perhaps just one or two. I'd like to try all of them but that would be quite expensive.
I really don't know, i just wanted to increase body hairs in my legs, belly, and face, i wanted too look more masculine, and reading in others forums i decided to try these ones. My head hair was an added bonus. But i can tell you that women look at me more often including younger ones, my wife told me that it seems that she is dating a new man, and our i timacy had improved, better erections ang long lasting ejaculation. 11 keto is a must have for me, if i have to chose only 2, i wiil stay with 11 keto dht and kuinone. You feel like a real nan with those two. Some users report that a product called pansterone has the same benefits, but its too expensive for a 1 month use. Think of this, 11 keto dht has 260 drops and you only apply 5 drops every other day, so it will last almost 4 months, and same goes to kuinone, 700 drops and you only need to apply one drop everyday, so it will last almost one year, so in reality it is cheap to buy those 2.
 

CheckMate

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May 11, 2020
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No side effects, 3 drops cortinon, 2 drops pregnenolone, 2 drops calcirol in the mornings. Then 2 drops pregnenolone, 2 drops calcirol in the afternoons. 11 keto dht 5 drops every other day. Tyromix 2 drops after a heavy cholesterol meal. But you know what is the wonder? I used to be lactose intolerant and i cant tell you wich supplement fixed the problem but now a can drink a gallon of milk without worrying about diarrhea. You need to try what works for you through trial and error.
Do you think using cream(pregnenolone, progesterone, dhea) is the same? where i live i can't get haidut productsD:
 

Momado965

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No side effects, 3 drops cortinon, 2 drops pregnenolone, 2 drops calcirol in the mornings. Then 2 drops pregnenolone, 2 drops calcirol in the afternoons. 11 keto dht 5 drops every other day. Tyromix 2 drops after a heavy cholesterol meal. But you know what is the wonder? I used to be lactose intolerant and i cant tell you wich supplement fixed the problem but now a can drink a gallon of milk without worrying about diarrhea. You need to try what works for you through trial and error.

I thought you used some of those products on your head.
 

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