Enzyme question progesterone allopreg 3α-Hydroxysteroid dehydrogenase

MarcR

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What happens if here you example increase or decrease 3a HSD
Is progesterone affected too?
Like. Lets say 3a HSD gets modified so there is more Allopreg (THP) AND DHP, because it works in both directions. This would mean there is more progesterone too, because there is more DHP and 5ar does not need to convert progesterone into DHP as much
Is this thinking correct? Sry im a noob with this

This is not specific to SSRIs (which target a specific part of 3a HSD enzyme as I know), I mean in general what happens when you decrease/increase 3a-HSD, the whole thing
 
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