Enhancement of Lethal Action of Endotoxin in Mice by Triiodo

Edward

Member
Joined
Apr 20, 2013
Messages
134
Age
38
Enhancement of Lethal Action of Endotoxin in Mice by Triiodothyronine
https://docs.google.com/file/d/0B1wyy-g ... sp=sharing

Triiodothyronine enhances the lethal action of endotoxin in mice. It is postulated that this enhancement is associated with anoxia, caused by vasoconstriction and subsequent hypotension that is induced by the endotoxin; and the increased demand for oxygen that is produced by triiodothyronine.
 

kiran

Member
Joined
Aug 9, 2012
Messages
1,054
Re: Enhancement of Lethal Action of Endotoxin in Mice by Tri

So starch/fiber consumption is incompatible with a higher metabolism. That's interesting.
 

honeybee

Member
Joined
Jan 22, 2013
Messages
331
Re: Enhancement of Lethal Action of Endotoxin in Mice by Tri

Only starch causes endotoxin?
 

jyb

Member
Joined
Nov 9, 2012
Messages
2,771
Location
UK
Re: Enhancement of Lethal Action of Endotoxin in Mice by Tri

Could this be due to an artificially high dose of T3 or increased energy requirement issues, which wouldn't necessarily arise if T3 rose naturally as part of a healthy metabolism?
 

charlie

The Law & Order Admin
Joined
Jan 4, 2012
Messages
11,683
Location
USA
Re: Enhancement of Lethal Action of Endotoxin in Mice by Tri

So artificial T3 supplementation increases endotoxin damage?
 

kiran

Member
Joined
Aug 9, 2012
Messages
1,054
Re: Enhancement of Lethal Action of Endotoxin in Mice by Tri

jyb said:
Could this be due to an artificially high dose of T3 or increased energy requirement issues, which wouldn't necessarily arise if T3 rose naturally as part of a healthy metabolism?

I would imagine that natural T3 would naturally dial itself back in the presence of endotoxin. Sugar may be protective against endotoxin, but this study doesn't cover that.
 

charlie

The Law & Order Admin
Joined
Jan 4, 2012
Messages
11,683
Location
USA
Re: Enhancement of Lethal Action of Endotoxin in Mice by Tri

It says cortisol increases to protect against the endotoxin. I wonder if that is why a lot of us are getting more stomach fat?
 

Edward

Member
Thread starter
Joined
Apr 20, 2013
Messages
134
Age
38
Re: Enhancement of Lethal Action of Endotoxin in Mice by Tri

A lot of people have issues with endotoxin caused by the tight junctions in the GI tract being compromised. When the gut is sound endotoxin is less of an issue and more so a fact of life. You can think of it like a leaky copper water pipe. When the water pipe is intact the water goes out were it is supposed to, when it is leaky some goes out where it is supposed to and some leaks to the outside and corrodes it and over time the leak becomes worse and worse usually causing structural damage to the house the pipe is in. Cortisol protects the organism temporarily but chronically one aspect a larger abdomen.

During an intravenous endotoxin challenge T3 and the other thyroid hormones drop in the blood. At first in the literature it wasn't clear if this was because the metabolism was increasing due to the challenge or because of an inhibitory effect, later it was found that it was indeed and inhibatory effect on the thyroid secreting the hormones.

The question still remains though, is this inhibitory effect a reaction to the endotoxin, or is endotoxin having a direct effect on the thyroid gland. The literature is mixed.

One more reason why it is important to solve as many problems as possible with nutrition before jumping on the thyroid supplement express to endotoxin city.
 
Similar threads
Thread starter Title Forum Replies Date
Lokzo My Testosterone Enhancement Journey - SOLVED Logs 55
noqcks Neurometabolic Mechanisms For Memory Enhancement And Neuroprotection Of Methylene Blue Scientific Studies 0
Lokzo Enhancement Of Serotonin Uptake By Cortisol Scientific Studies 8
raypeatclips Consequences Of Magnesium Deficiency On The Enhancement Of Stress (review) Scientific Studies 0
J Dopamine/Focus Enhancement Recommendations Mind, Sleep, Stress 66
H Cognitive Enhancement In Infants Associated With Increased Maternal Fruit Intake During Pregnancy Scientific Studies 0
Entropy Enhancement of Mammary Tumorigenesis by Dietary Selenium Deficiency in Rats with a High Polyunsatura Scientific Studies 0
haidut Keto Diet Can Cause Lethal Kidney Failure Scientific Studies 4
Lewis Acid Colonoscopy’s Are Lethal And Do NOT Detect Cancer Labs 7
burtlancast Mysterious Blood Clots Are COVID-19's Latest Lethal Surprise Miscellaneous Health Discussions 4
haidut Low-carb Diets May Cause Lethal Heart Rhythm Disorder (AFib) Scientific Studies 2
haidut Breaking News: Viagra Given To Pregnant Women Is Lethal For The Babies Scientific Studies 4
haidut Chemotherapy Causes Cancer To Spread And Makes It Lethal Scientific Studies 11
M Medical Establishment Conspiracy To Conceal Lethal Risks Of Common Medical Procedure! Articles & Scientific Studies 23
haidut DHEA protects from endotoxin (even lethal doses) Scientific Studies 1
haidut Blue light lethal to insects, while red / infrared is least harmful Light 0
L Reiner Fuellmich Files Class Action against Davis crowd for crimes against humanity Political Talk, Alternative World Theories 23
Energizer #ExposeBillGates Day Of Action 2 On August 8 Breaking News 14
F Overthinking And Worrying Cause Difficulties With Focus And Taking Action In The Present Moment Ask For Help or Advice 1
M 5 % CO(2) Has A Fast And Potent Anti-convulsant Action Scientific Studies 0
ScurveDream Isn't "the Shrinking Middle-class" Just A Form Of Polarization In Action? Political Talk, Alternative World Theories 39
L SSRI Impairs Minocyclins Antidepressive Action Articles & Scientific Studies 2
J Bioenergetic View Of Autoimmunity: Struggling To Understand Cortisol's Action Cortisol, Serotonin, Histamine 4
T Rhythmic Diurnal Synthesis And Signaling Of Retinoic Acid In The Rat Pineal Gland And Its Action To Scientific Studies 25
P Antiinflammatory Action Of Oral Baking Soda Articles & Scientific Studies 39
A Idiocracy - So Delicious Coconut Milk Class Action Challenges Health Claims Rant or Rave 14
General Orange Anti-inflammatory Action Of Coffee But Not Of Caffeine Consumption Scientific Studies 7
haidut The Progesterone-like Action Of Testosterone And Other Androgens Scientific Studies 8
H Estrogenic Endocrine Disruptors: Molecular Mechanisms Of Action Scientific Studies 11
P Statins May Exert Beneficial Effects Through A Pathway Other Than It's Cholesterol Lowering Action Articles & Scientific Studies 6
P Action Of Topical Thyroid Hormone Analogue In Reversing Glucocorticoid-induced Skin Atrophy Articles & Scientific Studies 22
R Maximize Action Of PDE 5 Inhibitors Male Issues 0
P Omega 7's Antiinflammatory Action On Ulcerative Colitis Patients Articles & Scientific Studies 2
L The Regulation Of Steroid Action By Sulfation And Desulfation Scientific Studies 0
Drareg Health Natura Threat Of Legal Action Ask For Help or Advice 23
keith Operation Pangea IX, FDA Action Targeting Internet Vendors Supplements, Pharmaceutical Drugs 0
P Dopaminergic Mechanism Of Antidepressant Action In Depressed Patients Scientific Studies 0
Drareg Deiodinases :implications Of The Local Control Of Thyroid Action Scientific Studies 4
P Ascorbate Is Essential For Dopamine Action To Inhibit Prolactin Release Scientific Studies 17
Velve921 Prolactin Information And Mechanism Of Action Ask For Help or Advice 1
haidut OTC Anti-histamines With Anti-serotonin Action Pharmaceutical Drugs 16
charlie Methylene Blue "...Action Involves Enhancing Mitochondrial Respiration by Supplementing The Action o Methylene Blue 1
goodandevil Antitussive Action Of Thc Articles & Scientific Studies 0
haidut The Randle Effect In Action (human Study) Macros & Micros 39
Edward The effect of caffeine on the antipyretic action of aspirin Articles & Scientific Studies 0
Amazigh Anxiety/PTSD/OCD: Prozac's Mechanism Of Action Is Normalization Of Allpregnanolone In The Brain Mind, Sleep, Stress 5
J Pro Thyroid Action Of Goitrogens Health 1

Similar threads

Top