Swandattur
Member
I have only seen the abstract. It sounds like endotoxin can exacerbate allergies and reactions to bacteria, though. http://onlinelibrary.wiley.com/doi/10.1 ... x/abstract. Here's what the abstract says: Keywords:
allergens;allergic;anti-IgE;asthma;bacteria;basophil leukocytes;endotoxins;histamine release;intrinsic asthma;lipopolysaccharides;non-immunological;potentiation
The histamine-releasing capability of lipopolysaccharides (LPS) was examined in human leukocyte suspensions. LPS alone did not release histamine, but was found to enhance the histamine release caused by anti-IgE. Also the IgE-mediated histamine release caused by specific antigens (allergens or bacteria) in sensitized individuals was enhanced by LPS. The potentiating effect of LPS was observed in grass pollen and dog dander allergic patients as well as in patients sensitized to E. coli or Staph, aureus bacteria. No potentiation was obtained by exposure to unspecific allergens or bacteria to which the persons were not sensitized. Bacteria can release histamine by immunological or nonimmunological mechanisms, and only the immunological histamine release was found to be potentiated by LPS. It is speculated that endotoxins reinforce release of histamine caused by allergens in allergic patients or by bacteria in persons sensitized to these microorganisms.
I notice if I eat any aged cheese, I will probably get an allergy reaction to my more allergenic cats, and if I don't eat cheese, I don't get a reaction. That may just be from the histamines in the cheese, but I guess the endotoxins in the cheese could play a role, too. Maybe the carrot salad would reduce the reaction.
allergens;allergic;anti-IgE;asthma;bacteria;basophil leukocytes;endotoxins;histamine release;intrinsic asthma;lipopolysaccharides;non-immunological;potentiation
The histamine-releasing capability of lipopolysaccharides (LPS) was examined in human leukocyte suspensions. LPS alone did not release histamine, but was found to enhance the histamine release caused by anti-IgE. Also the IgE-mediated histamine release caused by specific antigens (allergens or bacteria) in sensitized individuals was enhanced by LPS. The potentiating effect of LPS was observed in grass pollen and dog dander allergic patients as well as in patients sensitized to E. coli or Staph, aureus bacteria. No potentiation was obtained by exposure to unspecific allergens or bacteria to which the persons were not sensitized. Bacteria can release histamine by immunological or nonimmunological mechanisms, and only the immunological histamine release was found to be potentiated by LPS. It is speculated that endotoxins reinforce release of histamine caused by allergens in allergic patients or by bacteria in persons sensitized to these microorganisms.
I notice if I eat any aged cheese, I will probably get an allergy reaction to my more allergenic cats, and if I don't eat cheese, I don't get a reaction. That may just be from the histamines in the cheese, but I guess the endotoxins in the cheese could play a role, too. Maybe the carrot salad would reduce the reaction.