Effects Of Cyproheptadine On Bladder Cancer

[Orome]

Even more prove that serotonine and histamine are involved in such conditions. Everything that lowers them should be beneficial.
Analysis of the effects of cyproheptadine on bladder cancer through big data

Abstract
This study was designed to compare the efficacy of Cyproheptadine (CY) in patients with bladder cancer (BC) who received different therapeutic modalities. We used the database from a hospital in Taiwan for analysis. We included patients diagnosed as having bladder cancer from January 1, 2008, to December 31, 2017. The patient cohort comprised those who received different treatments, and we compared patients who received CY with those who did not. In total, 627 patients were included, and the mean follow-up duration was 3.26 years. All data were filtered out by 230 million data and 119 patients had used CY. Among them, 32 patients were used over 3 months of CY. The CY treatment curve shown by Kaplan-Meier survival curves for patients treated is higher than that of the non-CY effect. The value of Chi-squared statistic was 4.138 with associated p-value less than 0.05. Two survival curves shown by the result of the log rank test differ significantly. The grouping variable different treatments for non-CY and CY has a significant influence on survival rate. These results suggest that the use of CY may improve the survival rate of patients with BC.

 

[mrchibbs]

Aspirin and cyproheptadine are like the best medecines for treating and preventing GI-related diseases and cancer.

 

[ecstatichamster]

Great find. Thank you @Orome

 

[Peachy]

Thank you for this. Just found out my dad has bladder cancer and it’s helpful.

 

[Orome]

I would also look into FAO inhibitors (if not yet done):

Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer - PubMed

Tumor cells rely on aerobic glycolysis as their main energy resource (Warburg effect). Recent research has highlighted the importance of lipid metabolism in tumor progression, and certain cancers even turn to fatty acids as the main fuel. Related studies have identified alterations of fatty acid...

pubmed.ncbi.nlm.nih.gov

You should find plenty information on the forum .

All the best for your father.

 

[Peachy]

I would also look into FAO inhibitors (if not yet done):

Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer - PubMed

Tumor cells rely on aerobic glycolysis as their main energy resource (Warburg effect). Recent research has highlighted the importance of lipid metabolism in tumor progression, and certain cancers even turn to fatty acids as the main fuel. Related studies have identified alterations of fatty acid...

pubmed.ncbi.nlm.nih.gov

You should find plenty information on the forum .

All the best for your father.

Good thinking. Thanks so much!

 

[Peachy]

I would also look into FAO inhibitors (if not yet done):

Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer - PubMed

Tumor cells rely on aerobic glycolysis as their main energy resource (Warburg effect). Recent research has highlighted the importance of lipid metabolism in tumor progression, and certain cancers even turn to fatty acids as the main fuel. Related studies have identified alterations of fatty acid...

pubmed.ncbi.nlm.nih.gov

You should find plenty information on the forum .

All the best for your father.

Of course he’s on metformin which I’ve been trying to get him off of for years. I’ll have to think through the transition from fao stimulator to fao inhibitor. But this is a great study to bring to the doctors and start the conversation. Really appreciate this.