Ebola Ph Dependant Acidic Entry

[charlie]

Viral Infections are pH Sensitive
http://drsircus.com/medicine/viral-spread-ph-sensitive

Detection of Cell-Cell Fusion Mediated by Ebola Virus Glycoproteins
http://jvi.asm.org/content/80/6/2815.abstract

Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1367161/

 

[tara]

Interesting.
My current understanding is that:
- blood pH is usually tightly constrained between 7.35 - 7.45
- UpH can vary a lot, but for normal healthy functioning tends to be slightly on the acid side (article suggests 6.5-7)
- UpH roughly correlates with intercellular pH over time
- that fighting cancer and at least some viruses is easier at more alkaline levels
- possibly higher alkalinity may make it easier to retain and use vit -C (Reams/RBTI)

What I wonder is:
- What is the relation between extraacellular and intracellular pH?
- If blood is generally 7.35-7.45, why is it so infectious? Is this because blood pH measures the plasm, while infectivity has to do with the pH of the blood cells, which may be much lower?

I guess from this article, one could consider driving alkalinity up high 1-2 days a week when there seems to be risk of infection? Using baking soda and/or calcium carbonate etc? I would expect keeping it high all the time to have a bunch of negative effects.