I don't know either, but that's interesting - it certainly gives reason for caution with unnecessary use of diatomaceous earth.But it's interesting that this drastic impact on insulin and blood sugars had absolutely nothing to do with food. I don't know if it was due to silica being negatively charged, or because I may have disrupted biofilm with the hard microscopic surface area of diatomaceous earth, thus killing huge amounts of gram negative bacteria. It's also possible that I was chelating endotoxins from other places of the body. I know endotoxins have a negatively charged phosphate group, but I'm not a biochemist.
What I've read, and seems plausible to me till I come across a better explanation, is that DE is good at killing parasites because it's sharp edges literally cut them up, and that this effect is also directly mechanically damaging to the gut lining. If you damage the gut barrier, you'd presumably make it a lot easier for endotoxin to leak into the system.
If the main problem for the system is a heavy load of gut parasites, and there aren't effective metheods available that are gentler, this might be worth it. Otherwise, I'd be thinking twice.
DE is also used to kill external parasites, too, like fleas and wasps. It's obviously quite harsh.
I wouldn't want to be breathing in the dust, either.