Frankdee20
Member
So, it's clear that adaptations emerge when people take SSRIs then stop. This downregulation or desensitized receptor function, etc., have been implicated in Discontinuation Syndromes of antidepressants. Is anyone aware of similar manifestations occurring if we stop Tianeptine ? Obviously, one enhances 5ht metabolism and the other prevents it, so theoretically, any discontinuation occurs via opposite means.