Does Scalp Oil/Sebum Prevent New Hair Growth On Bald Heads ?

DMF

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Sep 5, 2012
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427
Hair has a way of "wicking up" scalp oil - up & away from the scalp making way or "room" for more oil to be secreted out,
So, when there is little or no hair, does the oil - or excess of it, have a way of possibly preventing new hairs from sprouting through -
suffocation maybe?
 

ChemHead

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Dec 8, 2020
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194
Definitely no. I've gotten my hair to grow and significantly thicken in diameter, while simultaneously also significantly increasing the oiliness of my skin and scalp. It's not an excess of some mysterious or ethereal substance (skin oil, androgens, etc.) that is preventing hair growth. It is an insufficiency of a particular substance. The reason why many people who suffer from hair loss have oily skin is because they lack sufficient aromatase expression and the testosterone that finds its way in those areas of the skin is not sufficiently metabolized to estrogens and instead is left to be as it is or be metabolized by 5-alpha reductase. The result is a region in the skin with insufficient estrogenic activity and excess androgenic activity.

Attenuation of the androgenic activity will not fix the problem because the problem isn't excess androgenic activity, it's insufficient estrogenic activity. This is why androgen receptor antagonists don't stimulate hair growth, but if estrogens are thrown in the mix, as in those who transition MTF, hair does, in fact, grow. A 5AR antagonist will work to a certain degree in hair growth stimulation because you're cutting off one of the two main enzymatic pathways in the skin that metabolize testosterone and that leaves behind aromatase as the only option. So, you end up with an excess of testosterone, which pushes the probability of aromatization higher and the result is excess testosterone and sufficient (but not more than sufficient) estrogens. Unfortunately, this type of environment is unsustainable because, while estrogenic activity is now sufficient in areas where it was formerly insufficient (e.g. hair follicles), it is now excessive in most other areas in the body (due to the systemic nature of finasteride), causing hypothalamic down regulation of both steroid synthesis and aromatase expression. This is the cause of finasteride losing its efficacy in many people (most, at some point).

So, no, excessively oily skin and scalp does not contribute to hair loss in any way. It's only a side effect of unfavorable balance of expression of testosterone metabolizing enzymes in the skin and hair follicles. Other than genetic engineering, the best approach for dealing with hair loss is to get your body to naturally synthesize higher levels of steroids (to push overall synthesis of all steroids higher, including estrogens, in the skin and hair), and to find substances that you can apply to the scalp to stimulate aromatase activity locally) without affecting the rest of the body). If you can lower 5AR expression in the scalp without affecting the rest of the body, whether by pharmaceutical or epigenetic intervention (diet, scalp massage, etc.), this will also help push the favorability of aromatization of testosterone higher.
 

MattJacko

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Joined
Feb 22, 2021
Messages
50
Definitely no. I've gotten my hair to grow and significantly thicken in diameter, while simultaneously also significantly increasing the oiliness of my skin and scalp. It's not an excess of some mysterious or ethereal substance (skin oil, androgens, etc.) that is preventing hair growth. It is an insufficiency of a particular substance. The reason why many people who suffer from hair loss have oily skin is because they lack sufficient aromatase expression and the testosterone that finds its way in those areas of the skin is not sufficiently metabolized to estrogens and instead is left to be as it is or be metabolized by 5-alpha reductase. The result is a region in the skin with insufficient estrogenic activity and excess androgenic activity.

Attenuation of the androgenic activity will not fix the problem because the problem isn't excess androgenic activity, it's insufficient estrogenic activity. This is why androgen receptor antagonists don't stimulate hair growth, but if estrogens are thrown in the mix, as in those who transition MTF, hair does, in fact, grow. A 5AR antagonist will work to a certain degree in hair growth stimulation because you're cutting off one of the two main enzymatic pathways in the skin that metabolize testosterone and that leaves behind aromatase as the only option. So, you end up with an excess of testosterone, which pushes the probability of aromatization higher and the result is excess testosterone and sufficient (but not more than sufficient) estrogens. Unfortunately, this type of environment is unsustainable because, while estrogenic activity is now sufficient in areas where it was formerly insufficient (e.g. hair follicles), it is now excessive in most other areas in the body (due to the systemic nature of finasteride), causing hypothalamic down regulation of both steroid synthesis and aromatase expression. This is the cause of finasteride losing its efficacy in many people (most, at some point).

So, no, excessively oily skin and scalp does not contribute to hair loss in any way. It's only a side effect of unfavorable balance of expression of testosterone metabolizing enzymes in the skin and hair follicles. Other than genetic engineering, the best approach for dealing with hair loss is to get your body to naturally synthesize higher levels of steroids (to push overall synthesis of all steroids higher, including estrogens, in the skin and hair), and to find substances that you can apply to the scalp to stimulate aromatase activity locally) without affecting the rest of the body). If you can lower 5AR expression in the scalp without affecting the rest of the body, whether by pharmaceutical or epigenetic intervention (diet, scalp massage, etc.), this will also help push the favorability of aromatization of testosterone higher.
Can you please share what you did to get your hair to grow and thicken?
 

ChemHead

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Joined
Dec 8, 2020
Messages
194
I used finasteride. But there's a particular way to use it that causes this effect and it's not worth doing... I don't recommend it. You essentially megadose it... Like at least 5 mg daily. What this does is that it very sharply causes a rise in plasma testosterone while aromatase expression is still high. This causes a very temporary sharp increase in intrafollicular estrogen synthesis. It will last for a few days at its peak and then sharply drop as the body downregulates aromatase expression. Then you're back to square one, plus you're steroid deficient due to hypothalamic dysregulation.
 
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