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member 6316
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I know Progesterone / Pregnenolone converts to allopregnanolone which helps with anxiety. But can DHEA convert to allopregnanolone or even THDOC?
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PeskyPeater
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DHEA's anxiolytic properties may result from the metabolism of DHEA to androsterone and 3a,5a-diol which are positive GABAA receptor modulators.
DHEA itself activates sigma-1 system and this has antidepressant and anti anxiety effects
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