Do positive allosteric modulators cause upregulation?

Feb 10, 2022

Astolfo

Member

PAMs do not directly bind to the agonist site but rather potentiate the signalling. So does this mean they cause "less agonism" on the receptor site and "upregulation" of that receptor?

Feb 13, 2022
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Astolfo

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Do positive allosteric modulators cause upregulation?

Astolfo

Member

Astolfo

Member

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