Andrew Kim
Diets rich in saturated and polyunsaturated fatty acids: metabolic shifting and cardiac health.
http://www.ncbi.nlm.nih.gov/pubmed/14962692
Diets rich in saturated and polyunsaturated fatty acids: metabolic shifting and cardiac health.
http://www.ncbi.nlm.nih.gov/pubmed/14962692
CONCLUSIONS:
PUFAs have been recommended as a therapeutic measure in preventive medicine to lower serum cholesterol, but PUFAs increased oxidative stress in the heart by providing cardiac susceptibility to lipoperoxidation and shifting the metabolic pathway for energy production. The control diet, which was much lower in calories and fat, produced better overall clinical outcomes, better fat profiles, and less oxidative stress than did the diets rich in fatty acids.