Adrenaline
Member
- Joined
- Sep 9, 2019
- Messages
- 96
Interesting study. DHT stimulates aromatase activity in human skin. Now, what's that supposed to mean?
Stimulation of aromatase activity by dihydrotestosterone in human skin fibroblasts. - PubMed - NCBI
Aromatase activity was stimulated 3- to 20-fold by DHT at concentrations 10(-10) and 10(-9) M. It was necessary to preincubate the cells with DHT for 48 h in order to bring about this stimulation.
This stimulatory effect was prevented by incubation of the cells with cycloheximide or actinomycin D, suggesting that DHT acts to increase aromatase activity in cultured fibroblasts by inducing the synthesis of new proteinaceous material.
Stimulation of aromatase activity by dihydrotestosterone in human skin fibroblasts. - PubMed - NCBI
Aromatase activity was stimulated 3- to 20-fold by DHT at concentrations 10(-10) and 10(-9) M. It was necessary to preincubate the cells with DHT for 48 h in order to bring about this stimulation.
This stimulatory effect was prevented by incubation of the cells with cycloheximide or actinomycin D, suggesting that DHT acts to increase aromatase activity in cultured fibroblasts by inducing the synthesis of new proteinaceous material.