IROM
Member
- Joined
- Feb 25, 2020
- Messages
- 154
Anyone have any clue about the musuclar dystrophy? My girlfriend's sister has the disease and I just want to know if Ray Peat has ever said anything about it. Is distrophin just a red herring? Most of what I see as symptomology is large amounts of pyruvate and lactate in the bloodstream which indicates a breakdown in the Krebs and Randall cycle.
@haidut had mentioned Acetoacetate cures MD in mice and that makes sense because Acetate =(acetyl-CoA) it is a direct precursor to ATP and it processes pyruvate which otherwise in excess would turn into lactate. I am coming from the Peatarian assumption that it is a metabolic disease and if sufficient ATP was produced the body would not catabolize muscle.
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Acetate is also required for proper fatty acid metabolism... and people with muscular dystrophy have abnormal fat tissue.
I think I am onto something but do not want to reinvent the wheel if this has already been discussed.
@haidut had mentioned Acetoacetate cures MD in mice and that makes sense because Acetate =(acetyl-CoA) it is a direct precursor to ATP and it processes pyruvate which otherwise in excess would turn into lactate. I am coming from the Peatarian assumption that it is a metabolic disease and if sufficient ATP was produced the body would not catabolize muscle.
Acetate is also required for proper fatty acid metabolism... and people with muscular dystrophy have abnormal fat tissue.
I think I am onto something but do not want to reinvent the wheel if this has already been discussed.