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DeFibron - Liquid Methylated SFA For Lab/R&D

Discussion in 'IdeaLabs' started by haidut, Jun 1, 2017.

  1. OP
    haidut

    haidut Member

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    Forgot the link to the thread.
    Simple, Non-invasive Method For Measuring PUFA Status
     
  2. brocktoon

    brocktoon Member

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    Hi, wondering if you can tell me what food or supplement you were referring to in this post that brought you the mentioned liver boosting benefits? Dessicated liver? Cooked liver? Or DeFibron? I have low glycogen storage and hope to improve my liver in this regard. Thanks.
     
  3. Spartan300

    Spartan300 Member

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    Thanks @haidut , I'm starting to think that PUFA depletion may be the right thing for me to focus on. My elevated IOP was detected but also occurred earlier than most. Following mainstream health advice by avoiding saturated fat for most of my adult life in favour of vegetable/sunflower oils/margarine etc make his scenario likely unfortunately.
     
  4. Fractality

    Fractality Member

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    How was the IOP detected? I'm curious to test mine. Thanks
     
  5. Spartan300

    Spartan300 Member

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    It was discovered whilst I was being treated for an injury where I had scratched the cornea in my right eye but a regular eye test at most opticians will include a pressure test.
     
  6. SQu

    SQu Member

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    Wow. What a great, easy, simple, cheap DIY idea!
     
  7. SQu

    SQu Member

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    A quick update ...
    As tested by the specialist, my husband's IOP that was 24 and 25 a month ago was 14 and 15 yesterday. He's been taking MCT for a few days, with an extra teaspoon an hour before testing. He's also been taking agmatine for 16 days. And a new prostaglandin eyedrop. Plus we dropped the cyproheptadine (he's missing that for a good night's sleep though) due to contra indications according to the package insert. So, MCT could be helping. Thanks for the idea. He's going to keep taking it daily.
     
  8. rebuke

    rebuke Member

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    Took 10 drops oral. Every meal for the rest of the day made me pass out shortly after. I guess this increases FFA?
     
  9. PecosRiver

    PecosRiver Member

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    Does topical application location matter? If I was concerned about heart fibrosis (or liver), would applying DeFibron as close to the organ being treated make a difference vs. putting drops on arms?
     
  10. nwo2012

    nwo2012 Member

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    I believe so, yes. There should be at least a short local effect before the substance goes systemic so it's definitely worth trying.
     
  11. OP
    haidut

    haidut Member

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    I don't think at 10 drops it increases FFA. Baseline lipolysis provides a lot more FFA than 10 drops of DeFibron would. The sleepiness could be from lower blood sugar, lower cortisol, lower serotonin, etc.
     
  12. Broken man

    Broken man Member

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    Please, are you using it orally or topically? Thank you.
     
  13. managing

    managing Member

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    If for hangover prevention/liver protection, that would definitely be most effective if swallowed.
     
  14. Owen B

    Owen B Member

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    I'm a little confused (probably a lot). I thought the fibrosis issue was connected with too much serotonin.

    Now, SFAs are OK too?

    Gonadin anti-fibrotic as well?
     
  15. OP
    haidut

    haidut Member

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    SFA have known anti-fibrotic effect. That's why they have been used to prevent/reverse liver fibrosis (cirrhosis) in human alcoholics. Not sure what the mechanism of action is exactly but displacing PUFA from the liver and reducing PUFA oxidation is one suggestion. I think serotonin opposition is also involved but not many studies have look at that.
     
  16. Hans

    Hans Member

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    MCT oil lowers TGFbeta, so maybe other saturated fat do too and this is one mechanism.
     
  17. BrianF

    BrianF Member

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    Defibron - does it matter much if its taken orally or. transdermally? My perspective is fibrosis of the lumg?
     
  18. Broken man

    Broken man Member

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    This is very interesting product, so just to be sure, when somebody´s rat will be using this product, the rat could be eating pufas without problems? Or is there some limit? Thank you.
     
  19. OP
    haidut

    haidut Member

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    I would not say PUFA can ever be eaten with zero problems, but DeFibron and tocopherol can probably decrease the risk from eating PUFA.
     
  20. Jackrabbit

    Jackrabbit Member

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    Hello, I’m wondering if you would please give us an update on your defibron use, are you still not using it, or did you feel the need to resume use? Do you think there were long term benefits from temporary use?
     
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