Grapelander
Member
Cypro seems to have an effect on cortisol thru serotonin pathway: Cyproheptadine caused significant decreases in mean plasma ACTH and cortisol levels in 30% and 19% of samples, respectively, mainly in the afternoon and evening. It did not lower in the morning; which is a good thing.does cyproheptadine inhibit 11b-HSD1 expression? (enzyme that converts cortisone to cortisol)
Emodin does inhibit 11b-HSD1 expression.