Curcumin (curry) Is Serotonergic

[ddjd]

maybe the anecdotal benefits about curcumin over the centuries comes from its cortisol inhibiting properties

Curcumin as a Potent and Selective Inhibitor of 11β-Hydroxysteroid Dehydrogenase 1

Curcumin as a Potent and Selective Inhibitor of 11β-Hydroxysteroid Dehydrogenase 1: Improving Lipid Profiles in High-Fat-Diet-Treated Rats

 

[Lokzo]

maybe the anecdotal benefits about curcumin over the centuries comes from its cortisol inhibiting properties

Curcumin as a Potent and Selective Inhibitor of 11β-Hydroxysteroid Dehydrogenase 1

Curcumin as a Potent and Selective Inhibitor of 11β-Hydroxysteroid Dehydrogenase 1: Improving Lipid Profiles in High-Fat-Diet-Treated Rats

This is exactly why I avoid it.

 

[ddjd]

This is exactly why I avoid it.

what you're trying to raise cortisol?

 

[Lokzo]

what you're trying to raise cortisol?

Yep.

Confirmed on my DUTCH test.... embarassingly low cortisol levels.

 

[Astolfo]

This is exactly why I avoid it.

Do you avoid from coffee too?

 

[ddjd]

Yep.

Confirmed on my DUTCH test.... embarassingly low cortisol levels.

what were your cortisol metabolites like? THE/THF? and more cortisone or cortisol metabolites?

 

[Dave Clark]

What exactly is the Dutch test? Is it just a saliva cortisol test, or is it a test that has more than just cortisol in the parameters, whether saliva or blood (or urine)? I saw on a Peat e-mail reply that he liked blood cortisol tests better than the saliva, but the post didn't elaborate as to why. I had a saliva cortisol test that showed below base line, but I am not sure I believe that I am deficient in cortisol. At the time, my doctor gave me hydrocortisone, and I didn't feel any better, so I quit that. Still trying to decide if most people that show low have a different problem, like receptor problems, etc., or HPA issues, etc.

 

[Mito]

What exactly is the Dutch test? Is it just a saliva cortisol test, or is it a test that has more than just cortisol in the parameters, whether saliva or blood (or urine)? I saw on a Peat e-mail reply that he liked blood cortisol tests better than the saliva, but the post didn't elaborate as to why. I had a saliva cortisol test that showed below base line, but I am not sure I believe that I am deficient in cortisol. At the time, my doctor gave me hydrocortisone, and I didn't feel any better, so I quit that. Still trying to decide if most people that show low have a different problem, like receptor problems, etc., or HPA issues, etc.

DUTCH = Dried Urine Test for Comprehensive Hormones (DUTCH Test – Advanced Hormone Testing), they use saliva for cortisol if you want the CAR (cortisol awakening response)

 

[Lokzo]

These are my results.

 

[Dave Clark]

Thanks for the graphics and link. I want to learn more about this for some other people, as well as myself.

 

[Mito]

View attachment 15424 View attachment 15425

These are my results.

Why do you describe your cortisol levels as embarrassingly low? Your free bioactive cortisone & cortisol are plenty good. Precision Analytical claims that free cortisol is the best proxy for tissue levels of cortisol. Your test suggests low metabolized cortisol (metabolites of both cortisol and cortisone so 11β-HSD1 doesn’t matter for this value). Precision Analytics claims that metabolized cortisol best represents overall cortisol production (accessing adrenal health). So wouldn’t your results suggest more of a problem with adrenal health (production) than any problem with 11β-HSD1 conversions?