CRISPR Epigenetics

[Drareg]

This is an introduction to using CRISPR to epigentically modify DNA,targeted methylation and acetyltion,they are using blue light in some cases as a signal for the CAS9 to follow, laser guided essentially.
I'm sure all of this has severe side effects they don't speak much of but we will see.
There is a lot of studies in this but this is just a basic introductory article from nature,best to take it with a pinch of salt.

CRISPR: gene editing is just the beginning

 

[lvysaur]

Can't wait until we see the first designer mice

 

[Drareg]

Can't wait until we see the first designer mice

http://www.nature.com/news/welcome-to-the-crispr-zoo-1.19537

 

[Drareg]

The title of this thread is wrong,the word epigenetics,the semantics around genetics needs to be changed,it's getting ridiculous.
Simple math,these 2 videos =?

 

[Drareg]

Something tells me they will ignore the importance of metabolism initially ,make mistakes but learn,whom will be the mistake,they should spot the increased feeding habits of creatures when edited.

Is it even possible to advance humans with super genes with the extra energy required,could you switch this off somehow? they could end with superman who needs to eat all day.

 

[Zpol]

Thank you for this thread Drareg.
I really appreciate you sharing your observation. Very good point.

 

[Giraffe]

FDA Approves First Gene-Edited Cows for Beef

In as little as two years, Americans could be biting into their first gene-edited burgers, courtesy of the U.S. Food and Drug Administration’s regulatory clearance of gene-edited cattle.

childrenshealthdefense.org

 

[Giraffe]

Maybe this one has been linked before?


Gene drive technology: what species should we make extinct today? -- Jon Rappoport

"The what-could-possibly-go-wrong question. As I’ve shown in past articles, the latest and greatest gene editing tools (e.g., CRISPR), which are used for gene drives, are far from slam-dunk precise, despite official assurances.

For example, Nature Communications, May 31, 2017, “CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.” Unintended genetic “deletions and insertions.”

And how about this study? It was published in Genome Biology on June 14, 2017, and is titled, “CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion.” An exon is “a segment of a DNA or RNA molecule containing information coding for a protein or peptide sequence.” So you can see that exon skipping or deletion is a very bad idea.

In other words, ANY gene editing done on ANY species opens the door wide to all sorts of errors and unforeseen consequences. Doomsday genetic warfare and mutually assured destruction are the far shore of insanity…but closer in, where the highly limited experiments are taking place, there is no safety zone, either. Insanity reigns there as well."

 

[Giraffe]

The European Commission plans to approve CRISPR/Cas genetically modified laying hens without risk assessment. As the rules are now the eggs would not even been labelled GM.

Das ethische Gentech-Ei -- Nachdenkseiten

"The intervention with the CRISPR/Cas gene scissors was developed at the Volcani Center, the research institute of the Israeli Ministry of Agriculture, which has also applied for a patent for the technique. In the process, a lethal gene is inserted into the chicken genome to be passed on only to the male offspring. The useless roosters would be gone - and we would finally have the genetically engineered eggs that seventy percent of Germans don't want."