Creatine

[Peatit]

If creatine increases water retention, isn't it a proof that it increases estrogen/cortisol/adrenaline/serotonin and reduces Carbon Dioxyde?

I'm inclined to think in the same way, it would be great if someone with good biochemical knowledge could chime in.

Synthesis of creatine and phosphatidylcholine are the two major consumers of methyl donors

Isn't it a good thing to consume methyl donors in order to limit DNA methylation for example?

 

[Drareg]

If creatine increases water retention, isn't it a proof that it increases estrogen/cortisol/adrenaline/serotonin and reduces Carbon Dioxyde?

Great insight, the research on DHT increasing as a result of creating use has not being replicated,I'm not sure the study was very good.
Peat was asked about creatine somewhere and he said he thinks it's safe? I'm not 100% though..
Creatine does have an effect though, by all accounts the loading phase is not necessary.

 

[AJC]

If creatine increases water retention, isn't it a proof that it increases estrogen/cortisol/adrenaline/serotonin and reduces Carbon Dioxyde?

I'm thinking that the increased water retention in this case refers specifically to muscle tissue and is mediated by increased ATP production. I think this is the reason people's muscles become "hard" (similar sounding to reports made in the 11-ketoDHT thread about the effects of DHT supplementation). This seems very different to me than the water retention in tissues in general (edema) due to stress hormones.

 

[Bahaa El wazzan]

I tried it

It's an amazing amino acid

I take 20 grams preworkout

3 days on and 3 days off

 

[Bahaa El wazzan]

30 grams creatine
3 days on
3 days off

For those who really workout

 

[cyclops]

Anyone taking creatine? Does it make your face puffy/bloated? Or is that a myth?

 

[BibleBeliever]

Anyone taking creatine? Does it make your face puffy/bloated? Or is that a myth?

I cycle it. I find it makes my quads a lot larger. Often deeper voice, stronger desire to work out and greatly increased sexual desire.
I have only seen steroid users get that weird puffy face thing, not sure what causes that.

 

[cyclops]

I cycle it. I find it makes my quads a lot larger. Often deeper voice, stronger desire to work out and greatly increased sexual desire.
I have only seen steroid users get that weird puffy face thing, not sure what causes that.

Nice results. What is your cycling schedule like? How much do you take?

 

[BibleBeliever]

Usually only 3-5 grams once or twice a day. Do it for a few weeks, then stop for a month or two. I only stop because the effects from it seem to diminish/stop.

 

[griesburner]

Usually only 3-5 grams once or twice a day. Do it for a few weeks, then stop for a month or two. I only stop because the effects from it seem to diminish/stop.

sounds good. interesting to hear a positive feedback on creatine. did you ever had heart related side effects like discussed in the following thread?
Creatine Fuels The Thermic Effect Of Feeding

 

[BibleBeliever]

sounds good. interesting to hear a positive feedback on creatine. did you ever had heart related side effects like discussed in the following thread?
Creatine Fuels The Thermic Effect Of Feeding

Never any side effects like that.
Not sure what mechanism could cause that side effect. Wonder if taurine, which is heart-protective would help.

 

[Amazoniac]

Creatine supplementation prevents fatty liver in rats fed choline-deficient diet: a burden of one-carbon and fatty acid metabolism
@Mito @paymanz @Tarmander
__
By the same priest:
Insulin Resistance

Insulin Resistance​

 

[Tarmander]

Creatine supplementation prevents fatty liver in rats fed choline-deficient diet: a burden of one-carbon and fatty acid metabolism
@Mito @paymanz @Tarmander
__
By the same priest:
Insulin Resistance

Insulin Resistance​

Pretty interesting. I do coffee everyday though, so I think Creatine is out for me.

 

[Mito]

Creatine supplementation prevents fatty liver in rats fed choline-deficient diet: a burden of one-carbon and fatty acid metabolism

About 40-45% of methylation is used to synthesize creatine, and another 40-45% is used to synthesize phosphatidylcholine. So in theory we could accomplish the same thing by supplementing phosphatidylcholine (i.e. MitoLipin)?

 

[Amazoniac]

www.suppversity.blogspot.com/search/label/creatine

 

[tca300]

www.suppversity.blogspot.com/search/label/creatine

Funny, I Just read that the other day.
Also my thoughts are if creatine and caffeine have bad effects on the system when introduced together, that would ultimately mean caffeine is bad and needs to be avoided since we synthesize creatine anyways.

 

[Amazoniac]

Funny, I Just read that the other day.

Guru, I meant his various posts on creatine. He has many!

 

[cyclops]

that would ultimately mean caffeine is bad and needs to be avoided since we synthesize creatine anyways.

Well that just can't be.

 

[tca300]

Well that just can't be.

I hope not... but my reasoning is likely flawed.

 

[superhuman]

creatine is good and the most research supplement. Just take 3-5g daily then you want get all the bloating and water retention. It will take longer to fully saturate the stores but make it much better and comfertable