Creatine

sctb

Member
Joined
Nov 7, 2012
Messages
61
There is a bunch of information here, with links to studies:

http://examine.com/supplements/Creatine/

In short, it participates in cellular energy production by donating a
phosphate to ADP in order to produce ATP. I can't really comment
on it other than to say that in general energy production is good :)

- Scott
 

gretchen

Member
Thread starter
Joined
Nov 30, 2012
Messages
816
sctb said:
There is a bunch of information here, with links to studies:

http://examine.com/supplements/Creatine/

In short, it participates in cellular energy production by donating a
phosphate to ADP in order to produce ATP. I can't really comment
on it other than to say that in general energy production is good :)

- Scott

Doesn't it contain amino acids that should be restricted like methionine?
 

dietf***ed

Member
Joined
Jan 20, 2013
Messages
31
Creatine is very commonly used in bodybuilding and is a very popular supplement for strength and lean mass. As long as you do not have a pre-existing kidney issue, I believe it is safe to ingest in its pure form without additives.
 

SoloX

Member
Joined
Mar 13, 2013
Messages
5
Jenn is involved in some naturalistic fallacy.

dietf**d is involved in poor knowledge - there is zero proof creatine causes any issues with your kidneys.
 

cliff

Member
Joined
Jul 26, 2012
Messages
425
Age
32
Location
Los Angeles
Heavy metal contamination is a concern with creatine, if you can get creapure it's tested for heavy metal content. I took creatine at one time and honestly I think it's just a waste of cash, you probably make all you need if you eat the right foods.
 

SoloX

Member
Joined
Mar 13, 2013
Messages
5
cliff said:
Heavy metal contamination is a concern with creatine, if you can get creapure it's tested for heavy metal content. I took creatine at one time and honestly I think it's just a waste of cash, you probably make all you need if you eat the right foods.

sctb's link clearly shows how much you would need to eat to get it via diet.
 

cliff

Member
Joined
Jul 26, 2012
Messages
425
Age
32
Location
Los Angeles
SoloX said:
sctb's link clearly shows how much you would need to eat to get it via diet.

Your body makes creatine from protein, you don't need to get it from diet.
 

SoloX

Member
Joined
Mar 13, 2013
Messages
5
cliff said:
In healthy people it's fine solox but there is evidence it may be harmful if you have kidney issues http://europepmc.org/abstract/MED/9643752

I know you probably take it and think it's the shiznit but you should use google before you call people out :p

Perfect example of how a little bit of knowledge is dangerous.

That is what is called a case-study. There was no analysis done on his consumption before nor after. It's not even a correlation or an example of transitive property.

But if you want to play with some actual double blind studies:

http://www.ncbi.nlm.nih.gov/pubmed/15569335
http://www.ncbi.nlm.nih.gov/pubmed/15795816
http://www.ncbi.nlm.nih.gov/pubmed/16260971
http://www.ncbi.nlm.nih.gov/pubmed/18188581
http://www.ncbi.nlm.nih.gov/pubmed/18780799
http://www.ncbi.nlm.nih.gov/pubmed/19403955
http://www.ncbi.nlm.nih.gov/pubmed/20976468

And if you want to play the singular case-study, here's someone with one functioning kidney (which also happens to be damaged): http://www.ncbi.nlm.nih.gov/pubmed/20060630
 

cliff

Member
Joined
Jul 26, 2012
Messages
425
Age
32
Location
Los Angeles
You said there is no evidence but I found evidence. I could care less how weak it is, you have to look at everything.
 

cliff

Member
Joined
Jul 26, 2012
Messages
425
Age
32
Location
Los Angeles
http://europepmc.org/abstract/MED/16509464
"Given the rarity of clinically significant rhabdomyolysis with this type of operation, we suggest that the patient's use of creatine increased the risk of skeletal muscle injury due to ischemia from intra-operative tourniquet application. "
http://www.nejm.org/doi/full/10.1056/NE ... 3113401017
"This case of acute interstitial nephritis should serve as a warning that the use of creatine, which is freely available in stores, may be associated with renal injury."
http://www.ncbi.nlm.nih.gov/pubmed/10609446
"Because commercially marketed creatine products do not meet the same quality control standards of pharmaceuticals, there is always a concern of impurities or doses higher or lower than those on the labeling. Consumers should balance the quality of information supporting the use of creatine with the known and theoretical risks of using the product, including possible renal dysfunction."
http://www.sciencedirect.com/science/ar ... 8601257552
"These results indicate that creatine supplements may exacerbate disease progression in an animal model of cystic renal disease. Although systematic research of the effects of creatine supplementation in humans with compromised renal"
http://www.sciencedirect.com/science/ar ... 760600104X
 

cliff

Member
Joined
Jul 26, 2012
Messages
425
Age
32
Location
Los Angeles
You seem to be confused as to what qualifies as proof.

If you said there is no double blind studies showing creatine causes renal issues you might be correct.
 

SoloX

Member
Joined
Mar 13, 2013
Messages
5
Okay you win. You seem to have made this personal instead of focusing on actual facts.
 

sctb

Member
Joined
Nov 7, 2012
Messages
61
I have taken creatine in the past, because in the more mainstream circles it's
touted as "cheap and effective, just take it", but I do not any longer. I'm with
cliff on this one -- although it might not be present in food in the same amounts
as you would get with supplementation, I think that the amount in food is
sufficient.

- Scott
 

slayers

Member
Joined
Oct 28, 2012
Messages
165
I have used creatine and it definitely works.
Ray peat said creatine is fine to take as long as you get it from a clean manufacture
 

mariange

Member
Joined
Jul 9, 2013
Messages
27
I was also curious about creatine after hearing (somewhat in passing) Ray Peat mention it on the Politics and Science Radio interview (It's from the one in 2012 titled "Autoimmune and Movement."

Has anyone found a "clean manufacturer"?
 
Similar threads
Thread starter Title Forum Replies Date
Lokzo Creatine Exerts Same Effects As Ketamine In The Brain? Scientific Studies 6
L Creatine‘s effects at TLR4-7 Supplements 2
Drareg Creatine Solubility Metabolism 0
Drareg Creatine Lowers Myostatin Scientific Studies 7
maillol Creatine Reduces Hepatic TG Accumulation (but Increases FAO) Supplements, Pharmaceutical Drugs 2
Frankdee20 Good Dose Of Creatine ? Not For Pumping Iron Ask For Help or Advice 8
H Novel Targets For Fast Antidepressant Responses (Creatine, Agmatine, Guanosine, Ascorbic Acid) Supplements 1
D Kidney Health - High Creatine And High Uric, GFR 80 Male Issues 12
ddjd Creatine Blunts Serotonergic Effects Of Methylene Blue And Caffeine Ask For Help or Advice 55
ddjd Creatine Stops Stress Reaction To Coffee Ask For Help or Advice 16
T Comprehensive Profiling Of Amino Acid Response Uncovers Methionine-Deprived Response. Creatine Scientific Studies 5
Rachel Using Urea And Creatine As A Cancer Treatment Cancer 10
dfspcc20 Creatine And Muscle Cramps Supplements, Pharmaceutical Drugs 31
B Niacinamide Enhances Creatine Neuroprotectiveness Against NMDA Agonist Toxicity Scientific Studies 4
L Oral Creatine Supplements Lower Plasma Homocysteine Concentrations In Humans Scientific Studies 0
P Creatine Fuels The Thermic Effect Of Feeding Articles & Scientific Studies 8
Adrian CREATINE AND DHT Supplements, Pharmaceutical Drugs 19
L Lowering Methylation Demand By Creatine Supplementation Paradoxically Decreases DNA Methylation Scientific Studies 2
D Creatine Raises DHT Or No? Supplements, Pharmaceutical Drugs 3
Deadpool What About Creatine? Supplements, Pharmaceutical Drugs 3
I Creatine Metabolism And Psychiatric Disorders: Does Creatine Supplementation Have Therapeutic Value? Scientific Studies 2
L Creatine Increases DHT Without Lowering Testosterone Supplements 0
TubZy Topical Creatine For Hair Health 15
P The Role Of Dietary Creatine Articles & Scientific Studies 14
P Creatine, Similar To Ketamine, Counteracts Depressive-Like Behavior Induced By Corticosterone Via PI Articles & Scientific Studies 5
P Evidence For The Involvement Of 5-HT1A Receptor In The Acute Antidepressant-like Effect Of Creatine Articles & Scientific Studies 10
Drareg Effects Of Creatine Supplementation On Oxidative Stress And Inflammatory Markers After Repeated-spri Scientific Studies 0
Drareg Effects Of Creatine Supplementation Associated With Resistance Training On Oxidative Stress In Diffe Scientific Studies 1
Drareg Short-term Creatine Supplementation Decreases Reactive Oxygen Species Content With No Changes In Exp Scientific Studies 0
Drareg Ammonia Toxicity To The Brain: Effects On Creatine Metabolism And Transport And Protective Roles Articles & Scientific Studies 25
P Creatine Supplementation As A Possible New Therapeutic Approach For Fatty Liver Disease Articles & Scientific Studies 1
P Creatine Treatment Promotes Differentiation Of GABA-ergic Neuronal Precursors In Cultured Fetal Rat Articles & Scientific Studies 1
P Exploratory Studies Of The Potential Anti-cancer Effects Of Creatine Articles & Scientific Studies 1
P A Creatine-driven Substrate Cycle Enhances Energy Expenditure And Thermogenesis In Beige Fat Articles & Scientific Studies 0
P Antidepressant-like Effect Of Creatine In Mice Involves Dopaminergic Activation Scientific Studies 15
sweetly Caffeine And Progression Of Parkinson Disease: A Deleterious Interaction With Creatine Cancer, Degenerative Diseases 47
A Creatine Recommendations? Supplements 4

Similar threads

Top