Hi All. Since I've heard haidut talking about Dr. Janci Chunn Lindsay and her concerns about the effects of vaccines on fertility (link here: Scientist makes inaccurate claims on Covid-19 vaccine safety) I started to track papers related to this subject.
I've found one study where they monitored pregnancies in women after COVID-19 vaccination (Pfizer and Moderna): https://perma.cc/R7WB-S2MW
This study needs longer follow up, but this is what they found out:" Among 3958 participants enrolled in the v-safe pregnancy registry, 827 had a completed pregnancy, of which 115 (13.9%) resulted in a pregnancy loss and 712 (86.1%) resulted in a live birth (mostly among participants with vaccination in the third trimester)."
This looks like the vaccine may be more dangerous in the first 2 trimesters and rather in the last one.
This part of the article was also interesting"
"Among pregnancy-specific conditions reported to the VAERS after Covid-19 vaccination, miscarriage was the most common. This is similar to what was observed during the influenza A (H1N1) pandemic in 2009 after the introduction of the 2009 H1N1 inactivated influenza vaccine, where miscarriage was the most common adverse event reported by pregnant persons who received that vaccine".
Based on this I've been looking if the miscarriage after vaccination (especially at the beginning of the pregnancy) could be related to the syncytin-1.
I've found this study: SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility.
SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility
"Vaccine hesitancy in reproductive-aged women has been heightened as a result of the spread of misinformation on social media stating that COVID-19 vaccines will cause sterility in women (1).
The proposed mechanism is the presumed similarity between the SARS-CoV-2 spike protein and syncytin-1 (2), a protein that is critical to the formation of the syncytiotrophoblast in a developing embryo (3). The hypothetical ensuing immune cross-reactivity would result in damage to the developing trophoblast, thereby preventing embryo implantation. If true, then this crossreactivity
would cause sterility not just from vaccination but also from natural illness and would be lifelong."
This is what they concluded:
"We have documented, for the first time in women, that seropositivity to the SARS-CoV-2 spike protein, whether from vaccination or infection, does not prevent embryo implantation or early pregnancy development".
In my opinion the study was too small (n=143) to make such a a strong claims about the vaccine safety. Here are the numbers:
Other thing is that - even if the conclusions from the study are correct and the vaccine does not affect syncytin-1 or implantation - it may still cause misarrange because of the inflammation that it is causing. Would you guys agree? Can anyone comment on this subject? Every opinion matters:)
I've found one study where they monitored pregnancies in women after COVID-19 vaccination (Pfizer and Moderna): https://perma.cc/R7WB-S2MW
This study needs longer follow up, but this is what they found out:" Among 3958 participants enrolled in the v-safe pregnancy registry, 827 had a completed pregnancy, of which 115 (13.9%) resulted in a pregnancy loss and 712 (86.1%) resulted in a live birth (mostly among participants with vaccination in the third trimester)."
This looks like the vaccine may be more dangerous in the first 2 trimesters and rather in the last one.
This part of the article was also interesting"
"Among pregnancy-specific conditions reported to the VAERS after Covid-19 vaccination, miscarriage was the most common. This is similar to what was observed during the influenza A (H1N1) pandemic in 2009 after the introduction of the 2009 H1N1 inactivated influenza vaccine, where miscarriage was the most common adverse event reported by pregnant persons who received that vaccine".
Based on this I've been looking if the miscarriage after vaccination (especially at the beginning of the pregnancy) could be related to the syncytin-1.
I've found this study: SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility.
SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility
"Vaccine hesitancy in reproductive-aged women has been heightened as a result of the spread of misinformation on social media stating that COVID-19 vaccines will cause sterility in women (1).
The proposed mechanism is the presumed similarity between the SARS-CoV-2 spike protein and syncytin-1 (2), a protein that is critical to the formation of the syncytiotrophoblast in a developing embryo (3). The hypothetical ensuing immune cross-reactivity would result in damage to the developing trophoblast, thereby preventing embryo implantation. If true, then this crossreactivity
would cause sterility not just from vaccination but also from natural illness and would be lifelong."
This is what they concluded:
"We have documented, for the first time in women, that seropositivity to the SARS-CoV-2 spike protein, whether from vaccination or infection, does not prevent embryo implantation or early pregnancy development".
In my opinion the study was too small (n=143) to make such a a strong claims about the vaccine safety. Here are the numbers:
Reactive Vaccine (n = 35) | Reactive infection (n = 20) | Nonreactive (n = 88) |
