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Conditionally Essential Amino Acids: Glycine And Arginine

Discussion in 'Amino Acids' started by Nicholas, Nov 13, 2015.

  1. Nicholas

    Nicholas Member

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    regarding Lysine overdosage:

    http://www.ncbi.nlm.nih.gov/pubmed/15204731

    "A Lys-related drop in serum concentration and an increase in urine excretion of chlorides was a compensatory reaction to the ingested hydrochloride. No functional, biochemical, or histological changes in renal function were found. The no-observed-adverse-effect level (NOAEL) for Lys was estimated at 5.0% for both genders (male, 3.36 +/- 0.12 g/kg/day; female, 3.99 +/- 0.28 g/kg/day)."

    regarding Taurine toxicity:

    http://www.ncbi.nlm.nih.gov/pubmed/18325648

    "The OSL risk assessments indicate that based on the available published human clinical trial data, the evidence for the absence of adverse effects is strong for Tau at supplemental intakes up to 3 g/d"

    regarding the antagonistic relationship of arginine and lysine:

    "Arginine is a conditionally essential amino acid, meaning that whether or not it is required to be healthy is conditional on the health status or life cycle of the individual." - wikipedia

    regarding lysine suppressing growth hormone in chicks, and arginine (or glycine) increasing it:

    http://jn.nutrition.org/content/104/9/1127.full.pdf

    glycine can increase growth hormone: http://www.ncbi.nlm.nih.gov/pubmed/23615880

    Glycine, like arginine, is a conditionally essential amino acid but also seems to show far more benefit (and even different benefit) than arginine.

    all of these points add up still to lysine being a low-risk supplement (along with Taurine, though not a true amino acid)....especially in situations where arginine depletion (and therefore GH and NO) is needed based on certain conditions somebody may be dealing with. also because Lysine is an essential amino acid.

    all this info. and other info shared in this forum also points to glycine and arginine being higher risk supplements based on the conditions of the person, while glycine seems lower risk than arginine supplementation.

    Growth hormone, NO, etc. are not evils to just assume that you need to lower. While interestingly, Lysine...an essential amino acid, does antagonize growth hormone and NO (Taurine does the same, but is not a true amino acid). If i'm mistaken, please share your perceptions and any other insight.
     
  2. hmac

    hmac Member

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    Interesting, thanks.
    Could you explain why Taurine isn't an amino acid?
     
  3. charlie

    charlie The Law & Order Admin

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    Thank you. :hattip
     
  4. NathanK

    NathanK Member

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    According to an Amazon review of Bulk Supps Ornithine, "Dr Oz show said that the Glycine, Ornithine, Arginine, and Lysine amino acids raise grown hormone levels by approximately 600%". I haven't had time, but was going to look into that claim.
     
  5. DaveFoster

    DaveFoster Member

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    Interesting how it's more for females, as males are heavier due to muscle mass.

    So that's 268 grams of lysine for an 80 kg man.
    :nonono
     
  6. Giraffe

    Giraffe Member

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    Peat doesn't recommend supplementing arginine: it's dangerous, stimulates cancer growth.

     
  7. Frankdee20

    Frankdee20 Member

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    I want to buy life insurance
     
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