COLLAGEN CONFUSION

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"Other things that protect against excessive polyamines are procaine and other local anesthetics (Yuspa, et al., 1980), magnesium, niacin, vitamin A, aspirin, and, in some circumstances, caffeine. Since endotoxin stimulates the formation of polyamines, a diet that doesn't irritate the intestine is important. Tryptophan and methionine contribute to the formation of polyamines, so gelatin, which lacks those amino acids and is soothing to the intestine, should be a regular part of the diet." -Ray Peat
 

aniciete

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fwiw:

My morning hot coffee latte is thus:

- 15g of gelatin (NOW brand – bloomed with ~ounce of milk)
- 2 tsp of cocoa (Bensdorp 22/24 Fat Dutched Cocoa)
- dash of salt
- 8 ounces of milk (heated in the microwave).
- 8 ounce of strong coffee (french pressed – fine ground)
- 2 tsp of molasses (Plantation Blackstrap Molasses, Organic)
- 1 tbsp of maple syrup (Local – New England)

I then have two more cold lattes later in the day but with no gelatin.

I do use a scoop of collagen to make my daily banana pancakes.

Here is the batter:

- 2 duck eggs
- 1/4 cup of non-fat powered milk (Bob's Red Mill)
- 1 scoop of Hydrolyzed collagen (Zen Principles)
- 1/4 tsp of salt
- 1/4 tsp of non-aluminum baking soda
Is that Bensdorp 22/24 Fat Dutched Cocoa any good? I recently learned that dutched is better and have been looking for a good brand.
 

amd

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Cadmium content in chocolate ..

Organic certification won't protect you from heavy metals.

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OP
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Cadmium content in chocolate ..

Organic certification won't protect you from heavy metals.

View attachment 34615
I am glad my chocolate isn’t on that list! I just had a piece a little bit ago. I am gonna repost your very helpful info!
 

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amd

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Only years from 2016 to 2018.
 
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“In my article on gelatin, I pointed out that the absence of methionine, cysteine, and tryptophan in gelatin made it especially beneficial in aging, because those amino acids, essential for growth in youth, contribute to inflammation and aging. A low methionine diet in rodents extended lifespan 40%.” -Ray Peat
 
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“These brands are made from grass-fed animals on pasture and raised without the use of antibiotics. They also have below 0.5 ug/day of lead and require no Prop. 65 Warning for California. We have some extensive notes to read with some specific companies down here as well to pay attention to. We linked up the brands we had verified by seeing labs.

 
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More from the linked article above….


“We made sure to include the results from this report in our overall findings below on collagen protein powders & best collagen supplements, but note that Ancient Nutrition, Bulletproof, Orgain & Preferred Elements had levels of lead above what the State of California recommends as safe. Ancient Nutrition, Correxiko, Orgain, Organixx, Reserveage Nutrition, & Vital Proteins had trace amounts of mercury. Bulletproof tested high for Cadmium.”
 
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@eggs are a highly nutritious way to get some extra collagen in your diet. Collagen is found in both the outer membrane (the one between the shell and the egg), and in the yolk. And while eggs are not considered to be a significant source of collagen, you will be getting some, plus you’ll also be getting protein, Vitamin E, B Vitamins and sulfur.”

 
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“Tryptophan, from dietary protein or from the catabolism of muscles, is turned into serotonin which activates the pituitary stress hormones, increasing cortisol, and intensifying catabolism, which releases more tryptophan. It suppresses thyroid function, which leads to an increased need for the stress hormones. Serotonin impairs glucose oxidation, and contributes to many of the problems associated with diabetes.” -Ray Peat
 
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“Keeping an optimal level of carbon dioxide (for example, when adapted to high altitude) causes calcium to be controlled, resulting in lowered parathyroid hormone, an effect similar to supplementing with calcium, vitamin D, and vitamin K. (E.g., Nicolaidou, et al, 2006.) Glycine, like carbon dioxide, protects proteins against oxidative damage (Lezcano, et al., 2006), so including gelatin (very rich in glycine) in the diet is probably protective.” -Ray Peat
 
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Rinse & rePeat:

“Should the tryptophan in milk be balanced with gelatin too or is there something in the milk that does that already?”

RAY PEAT:

“The antiinflammatory effects of milk proteins are usually enough.”
 
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This is interesting….


“While adding some collagen to your daily cup of coffee may seem like a natural way to supplement the powder in your diet, you may be better off using it in your morning smoothie or stirring it into a glass of water. An article by Texas A&M researcher Brooke Russell, Ph.D., says that collagen won't hold up in temperatures higher than body temperature, and the desired health benefits will either be diminished or completely negated—not exactly what we're looking for when a 20-ounce tub costs $35. This information is especially interesting considering that Vital Proteins also sells Collagen Creamers designed to bring some richness to your morning cuppa.“

 
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“The effect of various avocado and soybean oils on collagen metabolism in the liver was studied in growing female rats for 8 weeks and in day-old chicks for 1 week. In comparison with rats fed either refined avocado oil, refined or unrefined soybean oils, rats fed unrefined avocado oil showed a significant decrease in total collagen solubility in the liver, while there were no changes in total collagen, protein and moisture content. Chicks fed unrefined avocado oil as compared to those fed refined avocado oil also showed a decrease in hepatic total soluble collagen while hepatic total collagen remained unaffected. Electron micrographs and light-microscope examinations of rats' liver revealed collagen accumulation in the periportal location. This is suggestive of the early stages of fibrosis.”

 
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“Gelatin is used in tryptophan depletion studies

Tryptophan-depletion studies have been done for years, as a way to study the relationship between low serotonin and depression. Often a tryptophan-deficient amino acid mixture is used for this purpose. More recently, collagen and gelatin are being used.

Collagen and gelatin are an excellent source of these amino acids: proline, glycine, glutamine and arginine, but they do not contain the amino acid tryptophan.

This paper, Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats summarizes what we find in a number of studies that use gelatin for the purpose of lowering serotonin levels, in order to study the relationship between serotonin and behavior:

The essential amino acid tryptophan is the precursor of the neurotransmitter serotonin. By depleting the body of tryptophan, brain tryptophan and serotonin levels are temporarily reduced. In this paper, several experiments are described in which dose and treatment effects of acute tryptophan depletion (ATD) using a gelatin-based protein-carbohydrate mixture were studied in male and female Wistar rats.“

 
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“The simplest, nonessential, amino acid, glycine, has been found to protect against carcinogenesis, inflammation, fibrosis, neurological damage, shock, asthma, and hypertension. Increased glycine improves learning (Handlemann, et al., 1989; File, et al., 1999), glycine antagonists usually impair it. Its antitoxic and cytoprotective actions are remarkable. Collagen, besides being free of tryptophan, contains a large amount of glycine--32% of its amino acid units, 22% of its weight.

The varied antiinflammatory and protective effects of glycine can be thought of as an antiserotonin action. For example, serotonin increases the formation of TNF (tumor necrosis factor, also called cachectin), glycine inhibits it. In some situations, glycine is known to suppress the formation of serotonin. Antagonists of serotonin can potentiate glycine's effects (Chesnoy-Marchais, et al., 2000). People who ate traditional diets, besides getting a lower concentration of tryptophan, were getting a large amount of glycine in their gelatin-rich diet.

Gelatin, besides being a good source of glycine, also contains a large amount of proline, which has some antiexcitatory properties similar to glycine.“ Ray Peat
 
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