Coffee Reverses Liver Disease

haidut

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aguilaroja

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The study was a "meta-analysis" rather than original research. Here is the pubmed link, with the abstract's conclusion:

Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis. - PubMed - NCBI
Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis.
Kennedy OJ, Roderick P, Buchanan R, Fallowfield JA, Hayes PC, Parkes J.
Aliment Pharmacol Ther. 2016 Mar;43(5):562-74. doi: 10.1111/apt.13523.

"CONCLUSION: This meta-analysis suggests that increasing coffee consumption may substantially reduce the risk of cirrhosis."

Southampton University has a better publicity unit, since a meta-analysis from Chongqing Medical University, published last November drew similar and wider conclusions:

Coffee Consumption Decreases Risks for Hepatic Fibrosis and Cirrhosis: A Meta-Analysis
Coffee Consumption Decreases Risks for Hepatic Fibrosis and Cirrhosis: A Meta-Analysis.
Liu F, Wang X, Wu G, Chen L, Hu P, Ren H, Hu H.
PLoS One. 2015 Nov 10;10(11):e0142457. doi: 10.1371/journal.pone.0142457.

"CONCLUSION: Coffee consumption can significantly reduce the risk for hepatic fibrosis and cirrhosis."

Coffee is also associated with less gallstone disease:
Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease. - PubMed - NCBI
Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease.
Zhang YP, Li WQ, Sun YL, Zhu RT, Wang WJ.
Aliment Pharmacol Ther. 2015 Sep;42(6):637-48. doi: 10.1111/apt.13328.

"This study suggests that coffee consumption is related to a significantly decreased risk of gallstone disease."

Forum member halam discussed a previous study:
Coffee and gallstones | Ray Peat Forum

Coffee, (including decaf) is also associated with lower risk of death. Not dying seems to be fairly important in medical care.

Coffee consumption and total mortality: a meta-analysis of twenty prospective cohort studies. - PubMed - NCBI
Coffee consumption and total mortality: a meta-analysis of twenty prospective cohort studies.
Je Y, Giovannucci E.
Br J Nutr. 2014 Apr 14;111(7):1162-73. doi: 10.1017/S0007114513003814. Epub 2013 Nov 27.

"High decaffeinated coffee consumption was also found to be associated with a lower risk of death, but the data are limited. Our findings indicate that coffee consumption is associated with a reduced risk of total mortality."

Forum member icecreamlover cited a more recent study with similar findings:

"Conclusions—Higher consumption of total coffee, caffeinated coffee, and decaffeinated coffee was as | Ray Peat Forum
 
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lollipop

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The study was a "meta-analysis" rather than original research. Here is the pubmed link, with the abstract's conclusion:

Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis. - PubMed - NCBI
Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis.
Kennedy OJ, Roderick P, Buchanan R, Fallowfield JA, Hayes PC, Parkes J.
Aliment Pharmacol Ther. 2016 Mar;43(5):562-74. doi: 10.1111/apt.13523.

"CONCLUSION: This meta-analysis suggests that increasing coffee consumption may substantially reduce the risk of cirrhosis."

Southampton University has a better publicity unit, since a meta-analysis from Chongqing Medical University, published last November drew similar and wider conclusions:

Coffee Consumption Decreases Risks for Hepatic Fibrosis and Cirrhosis: A Meta-Analysis
Coffee Consumption Decreases Risks for Hepatic Fibrosis and Cirrhosis: A Meta-Analysis.
Liu F, Wang X, Wu G, Chen L, Hu P, Ren H, Hu H.
PLoS One. 2015 Nov 10;10(11):e0142457. doi: 10.1371/journal.pone.0142457.

"CONCLUSION: Coffee consumption can significantly reduce the risk for hepatic fibrosis and cirrhosis."

Coffee is also associated with less gallstone disease:
Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease. - PubMed - NCBI
Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease.
Zhang YP, Li WQ, Sun YL, Zhu RT, Wang WJ.
Aliment Pharmacol Ther. 2015 Sep;42(6):637-48. doi: 10.1111/apt.13328.

"This study suggests that coffee consumption is related to a significantly decreased risk of gallstone disease."

Forum member halam discussed a previous study:
Coffee and gallstones | Ray Peat Forum

Coffee, (including decaf) is also associated with lower risk of death. Not dying seems to be fairly important in medical care.

Coffee consumption and total mortality: a meta-analysis of twenty prospective cohort studies. - PubMed - NCBI
Coffee consumption and total mortality: a meta-analysis of twenty prospective cohort studies.
Je Y, Giovannucci E.
Br J Nutr. 2014 Apr 14;111(7):1162-73. doi: 10.1017/S0007114513003814. Epub 2013 Nov 27.

"High decaffeinated coffee consumption was also found to be associated with a lower risk of death, but the data are limited. Our findings indicate that coffee consumption is associated with a reduced risk of total mortality."

Forum member icecreamlover cited a more recent study with similar findings:

"Conclusions—Higher consumption of total coffee, caffeinated coffee, and decaffeinated coffee was as | Ray Peat Forum
Nice @aguilaroja !!
 

Makrosky

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Interesting that they explicitly mention COFFEE, not CAFFEINE. Even decaffeinated. That means taking caffeine pills is getting only a percentage of benefits.

Right?
 
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James IV

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As Dr Peat has mentioned before, coffee is much more than just caffiene. So your assumption is likely correct.

Edit* this is in response to Makroskys post above. Not sure what the quote post didn't work.
 
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docall18

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As Dr Peat has mentioned before, coffee is much more than just caffiene. So your assumption is likely correct.

Mmm, i dont seem to get as positive/pronounced effect from a very strong coffee as i do from a 200mg caffeine pill. Maybe its because the pill hits all at once, raising blood caffeine higher than a coffee.
 

tara

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James IV

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Mmm, i dont seem to get as positive/pronounced effect from a very strong coffee as i do from a 200mg caffeine pill. Maybe its because the pill hits all at once, raising blood caffeine higher than a coffee.

caffiene content is going to vary quite a bit from one cup of coffee to the next. But even a very strong cup of coffee is only likely to be 100mg or so of caffiene. So a 200mg pill would definitely hit you significantly harder.
 

Makrosky

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Is this due to the fact coffee helps the lvier metabolize fats mroe efficiently? Plus the magnesium?
I don't think the minerals/vitamins in coffee make any difference at all. I think it's the more than 1000 chemicals in coffee and the combination of them, like : caffeine, palmitic acid, cafestol, kahweol, diterpenes, chlorogenic acids, you name it.
 
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docall18

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caffiene content is going to vary quite a bit from one cup of coffee to the next. But even a very strong cup of coffee is only likely to be 100mg or so of caffiene. So a 200mg pill would definitely hit you significantly harder.

Coffee Caffine Content - mg
Dunkin' Donuts Coffee with Turbo Shot large, 20 fl. oz. 436
Starbucks Coffee venti, 20 fl. oz. 415
Starbucks Coffee grande, 16 fl. oz. 330
Panera Frozen Mocha 16.5 fl. oz. 267
Starbucks Coffee tall, 12 fl. oz. 260
Starbucks Caffè Americano grande, 16 fl. oz. 225
Panera Coffee regular, 16.8 fl. oz. 189
Starbucks Espresso Frappuccino venti, 24 fl. oz. 185
Dunkin' Donuts Coffee medium, 14 fl. oz. 178
Starbucks Caffè Mocha grande, 16 fl. oz. 175
Starbucks Iced Coffee grande, 16 fl. oz. 165
Maxwell House Ground Coffee—100% Colombian, Dark Roast, Master Blend, or Original Roast 2 Tbs., makes 12 fl. oz. 100-160
 
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James IV

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Coffee Caffine Content - mg
Dunkin' Donuts Coffee with Turbo Shot large, 20 fl. oz. 436
Starbucks Coffee venti, 20 fl. oz. 415
Starbucks Coffee grande, 16 fl. oz. 330
Panera Frozen Mocha 16.5 fl. oz. 267
Starbucks Coffee tall, 12 fl. oz. 260
Starbucks Caffè Americano grande, 16 fl. oz. 225
Panera Coffee regular, 16.8 fl. oz. 189
Starbucks Espresso Frappuccino venti, 24 fl. oz. 185
Dunkin' Donuts Coffee medium, 14 fl. oz. 178
Starbucks Caffè Mocha grande, 16 fl. oz. 175
Starbucks Iced Coffee grande, 16 fl. oz. 165
Maxwell House Ground Coffee—100% Colombian, Dark Roast, Master Blend, or Original Roast 2 Tbs., makes 12 fl. oz. 100-160

Ah, you mean the modern version of a cup of coffee, which is a bucket of coffee with added shots of caffeine. Yes, in that case the caffiene will be significantly more than an actual cup of standard brew coffee.
 

Peata

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Lots of things modify the risk of death in the next week or year, though.

:+1Yeah, I thought it was a given that we are here trying to improve health and quality of life as long as it lasts, and if coffee helps our livers, that's important.
 

sladerunner69

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I don't think the minerals/vitamins in coffee make any difference at all. I think it's the more than 1000 chemicals in coffee and the combination of them, like : caffeine, palmitic acid, cafestol, kahweol, diterpenes, chlorogenic acids, you name it.

Then why does coffee, in large amoutns consumed throughout the day, make me feel so anxious, tired and lsitless towards the end of the day? Regardless of what everyone says here, I cant drink coffee without the crash.
 
EMF Mitigation - Flush Niacin - Big 5 Minerals

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