Clarityn, Clarinex Vs Cyphroheptadine

[Beefcake]

Hi guys!

So got interested if drugs like clarityn and clarinex would have same mechanism as cyphroheptadine?

Their molecular structure are very similair since they are all anti-histamins based on trycyclic structure



Also found studies on ncbi that both
Clarityn and clarinex display anti serotonin properties. And one study they even used loratadine to countet the sexual side effects of SSRI with great success.

 

[LUH 3417]

What about their effect on water retention?

 

[Beefcake]

What about their effect on water retention?

I dont know about that im more speaking about them being easy access serotonin inhibitors. They also have anti cholinergic and antihistamine effects which all are ”peaty”

 

[methylenewhite]

Clarityn and clarinex display anti serotonin properties. And one study they even used loratadine to countet the sexual side effects of SSRI with great success.

Would you share a link please?

 

[Beefcake]

Would you share a link please?

An open-label series using loratadine for the treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors. - PubMed - NCBI

Effect of loratadine on immediate and delayed type hypersensitivity reactions. - PubMed - NCBI

The drug also caused an anti-acetylcholine, anti-serotonin and anti-leukotriene D4 (LTD4) effect. In addition, loratadine inhibited the synthesis of leukotrienes more potently than ketotifen.

The drug was more potent than ketotifen and terfenadine in inhibiting antigen-induced increase in airway resistance in guinea pigs.

Theres more. U can use search engines?