Cistanche increases steroidogenic enzymes, lowers NO, helps osteoporosis and Alzheimer's

[Ras]

That's possible , but I dont think its 10x more potent .

Are you affiliated with ND ?

I am not affiliated with ND in any way.

ND's product is 12 times more potent than that used in the study.

 

[MyUsernameHere]

Seems to be helping my hair yet increasing brain fog and anxiety right now, I feel like my PFS is coming back. Different reaction to before when it was making me angry, causing my hair to fall out and so on...

 

[Mauritio]

I am not affiliated with ND in any way.

ND's product is 12 times more potent than that used in the study.

OK good to know. How do you know that? And which study are we talking about ?

Seems to be helping my hair yet increasing brain fog and anxiety right now, I feel like my PFS is coming back. Different reaction to before when it was making me angry, causing my hair to fall out and so on...

It might decrease allopregnanolone. So taking it with 5adhp or other things that increase allopregnanolone might help.

 

[Ras]

OK good to know. How do you know that? And which study are we talking about ?

You wrote that animal studies used grams; I was talking about them. The linked comments from the ND subreddit touch on the same.

 

[Ismail]

Have you gotten around to try the TCM one by now?

Hey bud, apologies for the delayed response, been a little overwhelmed with my court cases.

Yes I've finally gotten round to using the tubulosa (the one I got from the TCM doctor), been using it for just under 10 days (3g every other day).

The taste is slightly different to that of the Jing herbs version, and the visual consistency is very different too (please see attached pictures). Jing herbs version is smooth and like a light brown colour, where as the TCM is like very small black-is granules (a bit like poppy seeds).

In terms of how I feel on the TCM (tubulosa) version, I'm still noticing the same beneficial skin effects as I did with the Jing version, as well as not breaking out anywhere (i.e. acne). The only slight difference I have noticed is that my libido has gone up ever so slightly since using the tubulosa version.

To be fair, I'm not sure how pure the TCM one is, even thought the doctor assured me it's very good quality "blah blah" etc.

I would like to try the 'Lost Empire Herbs' to see if there is any difference to that of the TCM version I'm using at the moment - have you or anyone else here used the lost empire herbs one? If so, how has it been for you? Is the consistency and colour the same as the Jing version (even though they are forms of cistanche)?

 

[GenericName86]

I would like to try the 'Lost Empire Herbs' to see if there is any difference to that of the TCM version I'm using at the moment - have you or anyone else here used the lost empire herbs one? If so, how has it been for you? Is the consistency and colour the same as the Jing version (even though they are forms of cistanche)?

Lost empire was the brand I used for tubulosa, i felt like it's a pretty good product, noticed it's effects quite quickly.

Looking at the Jing herbs picture you posted, my batch from lost empire was much darker in colour.

 

[Mauritio]

Hey bud, apologies for the delayed response, been a little overwhelmed with my court cases.

Yes I've finally gotten round to using the tubulosa (the one I got from the TCM doctor), been using it for just under 10 days (3g every other day).

The taste is slightly different to that of the Jing herbs version, and the visual consistency is very different too (please see attached pictures). Jing herbs version is smooth and like a light brown colour, where as the TCM is like very small black-is granules (a bit like poppy seeds).

In terms of how I feel on the TCM (tubulosa) version, I'm still noticing the same beneficial skin effects as I did with the Jing version, as well as not breaking out anywhere (i.e. acne). The only slight difference I have noticed is that my libido has gone up ever so slightly since using the tubulosa version.

To be fair, I'm not sure how pure the TCM one is, even thought the doctor assured me it's very good quality "blah blah" etc.

I would like to try the 'Lost Empire Herbs' to see if there is any difference to that of the TCM version I'm using at the moment - have you or anyone else here used the lost empire herbs one? If so, how has it been for you? Is the consistency and colour the same as the Jing version (even though they are forms of cistanche)?

Thanks for sharing mate !
Mine definitely looks a lot more like jing herbs version (raw forest foods)

 

[GenericName86]

Upon having a better look at my batch (haven't used it in a few weeks) It's certainly a dark brown but not as dark as the TCM version pic.

I should start using it again, my idea was to cycle it and I think it's time to use it again, especially after I was looking at your uncoupling thread @Mauritio and i remembered I saw a study showing cistanche extract showed evidence of uncoupled respiration

 

[Mauritio]

Upon having a better look at my batch (haven't used it in a few weeks) It's certainly a dark brown but not as dark as the TCM version pic.

I should start using it again, my idea was to cycle it and I think it's time to use it again, especially after I was looking at your uncoupling thread @Mauritio and i remembered I saw a study showing cistanche extract showed evidence of uncoupled respiration

Can you link that study ? I'd be interested to see which dosage is required.

 

[GenericName86]

Can you link that study ? I'd be interested to see which dosage is required.

Couldn't remember the exact study so just googled "cistanche uncoupling" and got bunch of results, think the first one here was the one I saw - https://www.tandfonline.com/doi/full/10.3109/13880200903190985 and here's another (PDF) Cistanches Herba reduces the weight gain in high fat diet-induced obese mice possibly through mitochondrial uncoupling

 

[Ismail]

Couldn't remember the exact study so just googled "cistanche uncoupling" and got bunch of results, think the first one here was the one I saw - https://www.tandfonline.com/doi/full/10.3109/13880200903190985 and here's another (PDF) Cistanches Herba reduces the weight gain in high fat diet-induced obese mice possibly through mitochondrial uncoupling

Wow! Thanks for this ??

 

[Ismail]

Thanks for sharing mate !
Mine definitely looks a lot more like jing herbs version (raw forest foods)

You’re very welcome as always bud ? ?

Upon having a better look at my batch (haven't used it in a few weeks) It's certainly a dark brown but not as dark as the TCM version pic.

I should start using it again, my idea was to cycle it and I think it's time to use it again, especially after I was looking at your uncoupling thread @Mauritio and i remembered I saw a study showing cistanche extract showed evidence of uncoupled respiration

Oh ok, thanks for sharing.

I wonder if it’s to do with the type of cistanche and/or the actual extraction method etc ??‍?

 

[Mauritio]

Couldn't remember the exact study so just googled "cistanche uncoupling" and got bunch of results, think the first one here was the one I saw - https://www.tandfonline.com/doi/full/10.3109/13880200903190985 and here's another (PDF) Cistanches Herba reduces the weight gain in high fat diet-induced obese mice possibly through mitochondrial uncoupling

Thanks. in the second study UCP3 increases about 67% in muscles at an HED of only 300mg daily !

 

[RenaissanceMan]

The net effect might still be pro DHT as it increases 5a-reductase 2 ,12 fold , so it might actually help with PFS.
Anyway I asked peat about his opinion on cistanche, and in particular the 5
a-reductase thing .

What did Peat say about Cistanche?

 

[Mauritio]

What did Peat say about Cistanche?

Nothing.

 

[Mauritio]

Cistanche improves constipation and helps gut wall/ cells .

Therapeutic effect of Cistanche deserticola on defecation in senile constipation rat model through stem cell factor/C-kit signaling pathway - PubMed

<span><i>C. deserticola</i> improved defecation in rats with constipation, and the SCF/C-kit signaling pathway, which is a key link of ICC function, played an important role of the treatment.</span>

pubmed.ncbi.nlm.nih.gov

Aqueous Extracts of Herba Cistanche Promoted Intestinal Motility in Loperamide-Induced Constipation Rats by Ameliorating the Interstitial Cells of Cajal

Traditional Chinese medicine was reported to have good effects in treating functional constipation. This work attempted to prove the effects of aqueous extracts of Herba Cistanche (AEHC) on STC treatment and to determine the possible mechanisms by a loperamide-induced ...

www.ncbi.nlm.nih.gov

 

[miquelangeles]

Cistanche improves constipation and helps gut wall/ cells .

Therapeutic effect of Cistanche deserticola on defecation in senile constipation rat model through stem cell factor/C-kit signaling pathway - PubMed

<span><i>C. deserticola</i> improved defecation in rats with constipation, and the SCF/C-kit signaling pathway, which is a key link of ICC function, played an important role of the treatment.</span>

pubmed.ncbi.nlm.nih.gov

Aqueous Extracts of Herba Cistanche Promoted Intestinal Motility in Loperamide-Induced Constipation Rats by Ameliorating the Interstitial Cells of Cajal

Traditional Chinese medicine was reported to have good effects in treating functional constipation. This work attempted to prove the effects of aqueous extracts of Herba Cistanche (AEHC) on STC treatment and to determine the possible mechanisms by a loperamide-induced ...

www.ncbi.nlm.nih.gov

I tried Cistanche for about 3 weeks and I kinda liked it.
But I think it messes with your immune system.
After the first week I developed something like a large cold sore on my lip which resolved within 2 or 3 days after stopping Cistanche, without leaving any sign.
I then resumed Cistanche and after another week I developed a nasty and painful ear infection which destroyed my sleep for a whole week and required antibiotics.
Makes me think it was not a coincidence. Cistanche polysaccharides have actually been proposed as adjuvants in vaccines.
I used the extract powder from Na'vi Organics, which is considered a reputable brand.

 

[Mauritio]

"...increased glycogen content (40.8% in liver and 52.6% in muscle, 200 mg/kg) and the activities of carbohydrate metabolizing enzymes; regulated lipid profile changes and the activities of antioxidant enzymes; diminished serum markers of oxidative stress and inflammation in a dose-dependent manner (p < 0.05)."

Therapeutic effect of Cistanche deserticola on defecation in senile constipation rat model through stem cell factor/C-kit signaling pathway - PubMed

<span><i>C. deserticola</i> improved defecation in rats with constipation, and the SCF/C-kit signaling pathway, which is a key link of ICC function, played an important role of the treatment.</span>

pubmed.ncbi.nlm.nih.gov

 

[Mauritio]

I tried Cistanche for about 3 weeks and I kinda liked it.
But I think it messes with your immune system.
After the first week I developed something like a large cold sore on my lip which resolved within 2 or 3 days after stopping Cistanche, without leaving any sign.
I then resumed Cistanche and after another week I developed a nasty and painful ear infection which destroyed my sleep for a whole week and required antibiotics.
Makes me think it was not a coincidence. Cistanche polysaccharides have actually been proposed as adjuvants in vaccines.
I used the extract powder from Na'vi Organics, which is considered a reputable brand.

Interesting, I have often experienced some form of detox reaction from cistanche, but I always thought it was due its anti-bacterial and anti-fungal effects. For example more dark circles the next day after taking it .
On the other hand I wonder why nobody else reported such effects, at least I havent read it and I think there's quite a few people that tried cistanche on this forum.
It could also be that helps your body fight an already existing infection ...

And I think the addition of cistanche to vaccines will likely make it safer, since cistanche known to be anti-inflammatory.

 

[Mauritio]

Cistanche reduces HIF :

Phenylethanol glycosides from Herba Cistanche improve the hypoxic tumor microenvironment and enhance the effects of oxaliplatin via the HIF‑1α signaling pathway - PubMed

Liver cancer is one of the most common types of malignant tumor, and is characterized by high malignancy, rapid progression, high morbidity and mortality. Oxaliplatin (OXA) has been reported to have marked efficiency against advanced liver cancer with tolerable toxicity. In solid tumors, the...

pubmed.ncbi.nlm.nih.gov