methylenewhite
Member
- Joined
- Aug 21, 2018
- Messages
- 1,237
Evaluation of Anti-Thyroid Activity of Hydro Alcoholic Extract of Coriander sativum in Experimental Animals.
https://www.rjpbcs.com/pdf/2018_9(1)/[45].pdf
Need help interpreting this study. Looks like title anti-thyroid activity is misleading. Im confused.
The group which received maximum test dose (500 mg/kg bw) showed maximum percentage increase in hormone concentration of T3 and T4 whereas a maximum percentage decrease in TSH levels was observed when compared to the lower dose levels, which clearly proves that the response was dose effective and Coriander sativum seeds extracts can be used in hypothyroidism condition to normalize hormone levels.
Histopathology studies of thyroid organ of the hyper thyroid instigated and treated rats were considered and were contrasted with control rats. The hyperthyroidism was observed in positive control animals due to increase of colloid in follicular epithelial cells and luminal colloids. The extracted treated animals demonstrated normal follicle lined by follicular epithelial cells. The findings indicate the hydroalcoholic extract of Coriander sativum seeds stimulant to thyroid functions.
https://www.rjpbcs.com/pdf/2018_9(1)/[45].pdf
Need help interpreting this study. Looks like title anti-thyroid activity is misleading. Im confused.
The group which received maximum test dose (500 mg/kg bw) showed maximum percentage increase in hormone concentration of T3 and T4 whereas a maximum percentage decrease in TSH levels was observed when compared to the lower dose levels, which clearly proves that the response was dose effective and Coriander sativum seeds extracts can be used in hypothyroidism condition to normalize hormone levels.
Histopathology studies of thyroid organ of the hyper thyroid instigated and treated rats were considered and were contrasted with control rats. The hyperthyroidism was observed in positive control animals due to increase of colloid in follicular epithelial cells and luminal colloids. The extracted treated animals demonstrated normal follicle lined by follicular epithelial cells. The findings indicate the hydroalcoholic extract of Coriander sativum seeds stimulant to thyroid functions.
