Choline: An Essential Nutrient for Public Health that we’re not getting enough of in our diet

[Ben.]

Not sure if it was mentioned already. Currently looking into mold/fungi infections more and was re-reading the PDF in the wondro thread and something caught my eye that might be worth mentioning in terms of candida albicans using acetaldehyde as a weapon:

"Acetylcholine is a significant neurotransmitter in both the peripheral and central nervous systemsresponsible for a host of functions including but not limited to mental concentration, memory, and sleeppatterns. Acetylcholine is synthesized in the body from dietary choline and acetyl-coenzyme A, aderivative of vitamin B5, by the enzyme choline acetyltransferase. Acetaldehyde has been shown toinhibit the production side but not the degradation side of acetylcholine thus creating a deficit in thisneurotransmitter."

If this has any truth to it then using alot of choline might not solve the issue.

 

[David PS]

Not sure if it was mentioned already. Currently looking into mold/fungi infections more and was re-reading the PDF in the wondro thread and something caught my eye that might be worth mentioning in terms of candida albicans using acetaldehyde as a weapon:

"Acetylcholine is a significant neurotransmitter in both the peripheral and central nervous systemsresponsible for a host of functions including but not limited to mental concentration, memory, and sleeppatterns. Acetylcholine is synthesized in the body from dietary choline and acetyl-coenzyme A, aderivative of vitamin B5, by the enzyme choline acetyltransferase. Acetaldehyde has been shown to inhibit the production side but not the degradation side of acetylcholine thus creating a deficit in thisneurotransmitter."

If this has any truth to it then using alot of choline might not solve the issue .

Thanks for the information. The main reason that I that i started this thread is that many people are not getting enough dietary choline. Nothing inhibits 'the production side' of making acetylcholine as quite like not having sufficient building blocks available to make adequate amounts.

Acetaldehyde exasperates this shortage of building blocks in many people. As LLight pointed out earlier in this thread, TMG might be a workaround for people who want to lower their choline requirements.

Not sure it really answers your question but eating foods high in betaine (aka Trimethylglycine or TMG) might lower the need for choline.

Edit - Not getting enough dietary choline is a 'supply chain issue' ---> production side issues.

 

[David PS]

This was posted today on YouTube. It is an interesting N=1.

View: https://www.youtube.com/watch?v=1Hh25TRG8p4

 

[Zsazsa]

This was posted today on YouTube. It is an interesting N=1.

View: https://www.youtube.com/watch?v=1Hh25TRG8p4

I didn't watch the video, but by the pictured frame he obviously used steroids

 

[Rinse & rePeat]

This was posted today on YouTube. It is an interesting N=1.

View: https://www.youtube.com/watch?v=1Hh25TRG8p4

This was interesting. I wonder why eggs got a bad rap in the 80’s?

 

[LadyRae]

View attachment 40170View attachment 40174
Here’s the old chicken coup. I think we could repair it and extend the run and hopefully be in for a decent supply of eggs.

Did you get chickens yet? Maybe this spring? I have 10. We actually converted the bottom of our kids playset into a coop... I can send you some pictures tomorrow. But you have a much better starting point than I had...

 

[Blossom]

Did you get chickens yet? Maybe this spring? I have 10. We actually converted the bottom of our kids playset into a coop... I can send you some pictures tomorrow. But you have a much better starting point than I had...

Not yet but I’m still hopeful my life will calm down enough that I can make it happen. Spring sounds like the perfect time to start! I’d definitely love to see your pictures.

 

[LadyRae]

Not yet but I’m still hopeful my life will calm down enough that I can make it happen. Spring sounds like the perfect time to start! I’d definitely love to see your pictures.

These are not impressive pictures but it's been pretty melty here lately... The bottom of the play set, which is the coop with two nesting boxes, connects to an outdoor run via a metal mesh tunnel... The kids still use the upper part and the swings in better weather.. we've been getting seven to nine eggs a day from our 10 hens. We have a photocell timer on a 250 watt yellow heat lamp bulb inside the coop.

I feed them chicken scraps, non-GMO dried black fly larvae, an organic chicken crumble feed, and raw beef liver several times a week. They also got some beef kidney and suet a few days ago.

I prepare placentas into dried gelatin capsules for new mothers, and I've been giving my chickens the umbilical cords which they eat like a giant worm. I know this is pretty Savage, I wonder what kind of comments I'll get from this LOL...

 

[Elie]

Not sure if anyone on this thread related choline to high glucose levels (often goes hand in hand with fatty liver).
I saw a comment on one of Chris Masterjohn' Choline articles, who said that his folks, both type 2 diabetics, experienced recovery from 1100 mg or so of choline pills.
Thoughts? experiences?

 

[Blossom]

Savage, I wonder what kind of comments I'll get from this LOL...

Nature is savage though. I absolutely love your set up. It’s really creative. Thanks for sharing the pictures.

 

[Zsazsa]

Savage, I wonder what kind of comments I'll get from this LOL...

They are related to dinosaurs, right?

 

[LadyRae]

They are related to dinosaurs, right?

I'd say so, even if I was just going by behavior...

The egg machine that is chicken: it's fascinating to me how you can control the quality of the egg by the food going into the chicken so acutely. I think it would be so fun to have some sort of egg scrutinizing machine where one could see how the micronutrient levels change depending on what a chicken eats.

 

[David PS]

This is another nice story.

View: https://twitter.com/ArcheonAscended/status/1614761888931319809

 

[LadyRae]

This is another nice story.

View: https://twitter.com/ArcheonAscended/status/1614761888931319809

That is very sweet! There's nothing like a baby chick!
In our experience, once you have all the requirements for three chickens, you might as well get 10. The food and water and lighting and housing and straw etc!

 

[Rinse & rePeat]

This is another nice story.

View: https://twitter.com/ArcheonAscended/status/1614761888931319809

This should happen on a larger scale.

 

[David PS]

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks

Evidence suggests that environmental factors may contribute to Alzheimer’s disease (AD). The B-like vitamin choline plays key roles in body- and brain-related functions. Choline produced endogenously by the phosphatidylethanolamine N-methyltransferase (PEMT) enzyme in the liver is not sufficient...

www.biorxiv.org

 

[David PS]

Blast from the past, when our government had our health in mind.

 

[Frankdee20]

Livers have choline, peanut butter and broccoli also

 

[David PS]

 

[David PS]

Published: 07 March 2023

Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis - IOS Press​

Background: Choline alphoscerate (alpha glyceryl phosphorylcholine, α-GPC) is a choline-containing phospholipid used as a medicine or nutraceutical to improve cognitive function impairment occurring in neurological conditions including adult-onset de

content.iospress.com

Conclusion:​

α-GPC alone or in combination with donepezil improved cognition, behavior, and functional outcomes among patients with neurological conditions associated with cerebrovascular injury.