Cells Have Memory, And Memories Of Past Conditions Affect Future Response

Thanos

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In this study, we’ve demonstrated the genes in muscle become more untagged with this epigenetic information when it grows following exercise in earlier life, importantly these genes remain untagged even when we lose muscle again, but this untagging helps ‘switch’ the gene on to a greater extent and is associated with greater muscle growth in response to exercise in later life - demonstrating an epigenetic memory of earlier life muscle growth!” The research has important implications in how athletes train, recover from injury, and also has potentially far-reaching consequences for athletes caught cheating. Dr Sharples explained:
“If an athlete’s muscle grows, and then they get injured and lose some muscle, it may help their later recovery if we know the genes responsible for muscle 'memory’. Further research will be important to understand how different exercise programmes can help activate these muscle memory genes.” Mr Seaborne continued:
If an elite athlete takes performance-enhancing drugs to put on muscle bulk, their muscle may retain a memory of this prior muscle growth. If the athlete is caught and given a ban - it may be the case that short bans are not adequate, as they may continue to be at an advantage over their competitors because they have taken drugs earlier in life, despite not taking drugs anymore. More research using drugs to build muscle, rather than exercise used in the present study, is required to confirm this.”
hi everyone
look at these study

quote from study''When mice were briefly treated with steroids the muscle mass and number of nuclei increased. The drug was subsequently withdrawn for 3 months and the muscle mass returned to normal, but the excess cell nuclei persisted. When such muscles were subjected to overload they grew by 30% over 6 days while controls grew insignificantly.''the mice used were female but it looks like testosterone played the biggest role in muscle growth.It looks like drugs play significant role on epigenetic cell memory(at least in case of testosterone)
 
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