dand

Member
Joined
Jul 3, 2014
Messages
214
Feels like Christmas all over again :). It's in the queue and looking forward to trying !
 

Dhair

Member
Joined
Jul 29, 2015
Messages
874
@haidut Would this be a good alternative for lowering prolactin for someone who isn't comfortable using something like lisuride or bromo? What is a good starting dose for someone who is typically prone to overstimulation?
 

tallglass13

Member
Joined
Dec 29, 2015
Messages
510
Anyone got this yet then? Must be some initial impressions..

I ordered on friday night , hoping it would start shipping Saturday, but he didnt ship it till Monday, 3 days estimate...I should get it today.
 

dand

Member
Joined
Jul 3, 2014
Messages
214
Just dropped twenty drops onto my tongue. Will check back in when I'm levitating.
 

Lucenzo01

Member
Joined
May 17, 2016
Messages
347
I can attest that proline is great and highly underrated IMO. Alpha tocopherol succinate has been superior to every other E product I have tried and maybe the succinic acid has something to do with it. Smart combination overall.
 

Mito

Member
Joined
Dec 10, 2016
Messages
1,709
Our new product is finally here and it is "all about the ATP".
Since ATP has a high affinity for magnesium, would this supplement increase the need for dietary (or supplemental) magnesium?
 

haidut

Member
Thread starter
Joined
Mar 18, 2013
Messages
17,332
Location
USA / Europe
Is this the most dopaminergic product from Idealabs? How stable is it? Shelf life?

Don't know if it is the most dopaminergic, but when I use it over several days it is very reminiscent to dopamine agonists like lisuride or pramipexole. ATP is stable in solution as long as it does not become too acidic or basic. So, ideal pH is in the 5-7 range. Shelf life is mandated by the FDA to be no more than 12 months, as the product is liquid.
 

haidut

Member
Thread starter
Joined
Mar 18, 2013
Messages
17,332
Location
USA / Europe

haidut

Member
Thread starter
Joined
Mar 18, 2013
Messages
17,332
Location
USA / Europe
Since ATP has a high affinity for magnesium, would this supplement increase the need for dietary (or supplemental) magnesium?

If anything, it would probably decrease the need it as it would help retain it from the dietary sources you consume it from.
 

haidut

Member
Thread starter
Joined
Mar 18, 2013
Messages
17,332
Location
USA / Europe
@haidut Would this be a good alternative for lowering prolactin for someone who isn't comfortable using something like lisuride or bromo? What is a good starting dose for someone who is typically prone to overstimulation?

Possibly, since the two studies on dopamine/prolactin showed that the L-PGA/B6 combo both lowered prolactin and increased dopamine. I would start with the recommended dose, every other day. You can try every day but if you notice headache and overstimulation I would back off and try a lower dose or every other day.
 

Wagner83

Member
Joined
Oct 15, 2016
Messages
3,241
Don't know if it is the most dopaminergic, but when I use it over several days it is very reminiscent to dopamine agonists like lisuride or pramipexole. ATP is stable in solution as long as it does not become too acidic or basic. So, ideal pH is in the 5-7 range. Shelf life is mandated by the FDA to be no more than 12 months, as the product is liquid.
Regarding the dopamine boost, is there any reason to believe it is more sustainable long term (no down regulation) than other dopaminergic compounds ?
 

denise

Member
Joined
Oct 18, 2013
Messages
299
Yesterday afternoon I used 25 drops topically. I didn't notice anything obvious until about 4-5 hours later, when I started having some heart palpitations off and on for maybe 20 minutes. Just prior to this, I did start feeling an extreme sense of well-being, but I'm not sure how much of this to chalk up to the Cardenosine and how much to chalk up to the fact that I'd just had an amazingly good evening with my husband. It may have been a mix of both. Today, the few times I've needed to walk briskly (like to get in out of the rain), I've felt it in my heart/chest more than usual. Also, I woke up at 3:30 from a bad dream, and when I woke up for work, I was again having a stressful dream (I haven't been recalling dreams recently at all).

I'll probably wait a couple days and try a half dose first thing in the morning, to see if the response is the same.
 

dand

Member
Joined
Jul 3, 2014
Messages
214
So far so good for me. Had a nice dopaminergic boost and heightened sense of well being throughout the day. Slept like a baby. Took the full dose orally.
 

haidut

Member
Thread starter
Joined
Mar 18, 2013
Messages
17,332
Location
USA / Europe
Regarding the dopamine boost, is there any reason to believe it is more sustainable long term (no down regulation) than other dopaminergic compounds ?

The mouse study showed that even a tiny dose of 1 mg/kg Metadoxine, which is equivalent to 0.08mg/kg for a human, elevated dopamine more than 24 hours after taking it. Since Metadoxine is used for ADHD in humans, I suspect the effects is persistent enough to matter. And since the effect is increase in actual endogenous dopamine synthesis vs. dopamine agonism on receptors, I am hoping that there would be less risk of downregulation.
 

managing

Member
Joined
Jun 19, 2014
Messages
2,262
Interestingly succinic acid is taken as a menopause "remedy". And RP says that:

"Filatov found that stressed tissues of both plants and animals produce protective and stimulating substances, which can be extracted for medical use. He identified succinic acid as a component of his extracts. Szent-Gyorgyi found that succinic acid stimulates respiration, which might explain why it promotes synthesis of pregnenolone and related steroids. It and fumaric acid are now considered to be adaptogens. Since succinic acid safely chelates toxic heavy metals out of mitochondria, it might also safely carry copper into the mitochondria."
 
Similar threads
Thread starter Title Forum Replies Date
D Cardenosine And Chelation IdeaLabs 14
poilochio Approximately 2 Year Old Bottle Of Cardenosine Still Good? Supplements, Pharmaceutical Drugs 3
M Solban + Cardenosine (DIY Formula) Hair & Nails 2
Momado965 Liquid tcopherol source E 2
C Liquid Alternatives Water 11
Frankdee20 Anyone Try Examastane Liquid From Blue Sky ? Ask For Help or Advice 5
B Starch Makes Extremities Warm But Lowers Underarm Temp; Liquid Sugar Does The Opposite Metabolism 6
C Benadryl (generic) Liquid Adult Ingredients Pharmaceutical Drugs 3
SuperStressed Boiling Meat: Does It Leach The Muscle Protein Into The Liquid? Diet, Recipes 1
A Constipation, Liquid Stools. At The Same Time Ask For Help or Advice 2
ecstatichamster The Thread For People Making Their Own Liquid Supplements (progest-e Etc.) Supplements, Pharmaceutical Drugs 7
YamnayaMommy Instapot CARAMEL From Liquid Whey Leftover From Cottage Cheese Cheese 0
haidut CamphoSal - Liquid Camphoric Acid + Salol IdeaLabs 325
YamnayaMommy Nutritional Value Of Whey Liquid Discarded From Making Cottage Cheese? Diet 5
methylenewhite I'm Scared, Bad Luck Accident, Wild Bat Physiological Liquid Contact Ask For Help or Advice 20
K What's The Deal With Liquid Coconut Oil? Coconut Oil 10
S How To Make Liquid DHEA? DHEA 6
Viiiiyu Dont Drink Water Nor Much Liquid Food.Normal? Diet 0
jzeno Thoughts On Liquid Magnesium? Supplements, Pharmaceutical Drugs 20
haidut Pyrucet - Liquid (ethyl) Pyruvate/Aceatoacetate Mix IdeaLabs 396
yerrag What Is Transfat-Free PUFA Oils That Are Still Liquid At Room Temp? Polyunsaturated Fats, Seed Oils 41
L Thorne Research - Vitamin K2 Liquid (1 Mg/drop) - 30 Ml (Dosage, Expiration, Storage) K 7
haidut 6-keto P4 - Liquid 6-ketoprogesterone For Lab/R&D IdeaLabs 372
denise Easy Scalp Application Of Liquid Supplements Hair & Nails 6
haidut Magnoil - Liquid Magnesium IdeaLabs 400
Captain_Coconut Help, What Is The Stability Of Pregnenolone In Liquid? Pregnenolone 3
R Dietary Liquid Advice/Tips Diet 0
haidut Calcirol - Liquid Vitamin D3 IdeaLabs 331
haidut CortiNon - Liquid Progesterone/DHEA Mix IdeaLabs 268
lvysaur Has Anyone Here Tried "always Liquid" Coconut Oil? Coconut Oil 30
haidut Lanosterol - Liquid Lanosterol For Lab/R&D IdeaLabs 138
Mito Magnesium Glycinate Liquid Magnesium 7
J What's The Best Way To Take Liquid K2 For Dental Health? Supplements, Pharmaceutical Drugs 9
L Liquid Stool Digestion 5
haidut DeFibron - Liquid Methylated SFA For Lab/R&D IdeaLabs 430
haidut Gonadin - Liquid Steroid Optimizer For Lab/R&D IdeaLabs 822
Parsifal Improper Dropper Feeding Of Liquid Vitamin D Feared Responsible In Accidental Death Vitamins 30
haidut Cyproheptadine - Liquid Serotonin Antagonist For Lab/R&D IdeaLabs 343
gnosisphoenix Liquid Multivitamin And Sleep Issues Supplements, Pharmaceutical Drugs 1
haidut 5α-DHP - Liquid 5α-Dihydroprogesterone For Lab/R&D IdeaLabs 892
pimpnamedraypeat Getting Over Long-Term Effects Of Nembutol (Liquid Pentobarbital) Overdose Ask For Help or Advice 2
T Help, Accidentally Spilled Liquid T3 On Myself Ask For Help or Advice 23
haidut Metergoline - Liquid Serotonin Antagonist For Lab/R&D IdeaLabs 838
haidut Androsterone - Liquid Androsterone For Lab/R&D IdeaLabs 1814
S Liquid Supplement Drop Size Supplements, Pharmaceutical Drugs 0
haidut Lisuride - Liquid Lisuride For Lab/R&D IdeaLabs 555
haidut TyroMix - Liquid T3/T4 Mix For Lab/R&D IdeaLabs 824
m_arch For Those On Predominantly Liquid Diets Diet, Recipes 2
healthnatura Glass As An Option Is Now Available For All Liquid Products Health Natura 1
haidut Panquinone - Liquid Triquinoyl/Quinone Mix For Lab/R&D IdeaLabs 246

Similar threads

Top