Canine dewormer cures cancer ?

[mayweatherking]

Saw this on tiktok... seems to be first hand he's saying it helped him since it's some guy personally posting it. Pretty interesting, wonder if anyone knows the mechanism. Maybe something with killing the endotoxin is helping


View: https://vm.tiktok.com/ZMdfMyngj/

 

[Missenger]

Obi-wan said he was going to try it out and just kind of just disappeared going on about chemo. That was back a few years ago.

 

[Palerider]

Another survivor, treated with Fenbendazole (animal deworming agent). Diagnosed with terminal small cell lung cancer August 2016.
Alive and well June 10 2021. Recent scan was an all clear NED ("no evidence of disease").

"The canine medicine that I took was available over the counter from numerous pet medicine on-line sites. It is branded as Panacur C and the drug name is Fenbendazole."

"You know, we've known for decades that these anthelmintic class of drugs (meaning to destroy parasites in the intestines) could have possible efficacy against cancer, and in fact in the 80's and 90's there was a drug called Levamisole that was used on colon cancer and it is an anthelmintic drug".

I said, "Doc, if you have known for decades why hasn't more work been done on it?" His answer was honest. He said, "probably because of money...all of these drugs are far off-patent and nobody is going to spend a gazillion dollars to repurpose them for cancer.....only to have generic competition the next day."

The website is a phenomenal resource and inspiration.

THE CONSOLIDATED STORY PUBLISHED AS ONE ENTRY FOR EASE OF USE ON MOBIL

AUGUST 2016 Attitude is Everything has always been my mantra. It seems that the more troublesome an event or challenge I've faced, my natural defense mechanism

www.mycancerstory.rocks

 

[Riesensackteil]

An Anti-fungal?

 

[Mastemah]

Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways - Scientific Reports

Drugs that are already clinically approved or experimentally tested for conditions other than cancer, but are found to possess previously unrecognized cytotoxicity towards malignant cells, may serve as fitting anti-cancer candidates. Methyl N-(6-phenylsulfanyl-1H benzimidazol-2-yl) carbamate...

www.nature.com

 

[Braveheart]

A Drug Made for Animals and Taken by Humans to Treat Cancer: Fenbendazole - Cancer Treatments - from Research to Application

Blog and Forum on the dewormer drug Fenbendazole (Panacur C) use in Cancer, the application Protocol, the Dose & the Science behind why it may be effective.

www.cancertreatmentsresearch.com

Treatments

Our Story about Killing Stage Four Prostate Cancer with Fenbendazole & Artemisinin

www.killingcancer.net

Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways - Scientific Reports

Drugs that are already clinically approved or experimentally tested for conditions other than cancer, but are found to possess previously unrecognized cytotoxicity towards malignant cells, may serve as fitting anti-cancer candidates. Methyl N-(6-phenylsulfanyl-1H benzimidazol-2-yl) carbamate...

www.nature.com

 

[Missenger]

Treatments

Our Story about Killing Stage Four Prostate Cancer with Fenbendazole & Artemisinin

www.killingcancer.net

DeWayne began taking Fendbendazole and Artimisinin in November 2019, before he began chemo. After DeWayne was diagnosed with Stage IV metastatic Prostate Cancer we began to do research.

Sure is coincidental, people could always have similar problems though.

 

[Ben.]

Pretty interesting, wonder if anyone knows the mechanism. Maybe something with killing the endotoxin is helping

Effects of fenbendazole and vitamin E succinate on the growth and survival of prostate cancer cells
December 2011
Journal of Cancer Research and Experimental Oncology


"While parasites are the primary targets of benzimidazoles because of theiraffinity for non-mammalian microtubulin and rapidly dividing cells (Lacey and Gill, 1994), Mebendazole, a derivative of the Benzimidazoles, has been shown to selectively induce apoptosis in adrenocortical carcinoma in vivo and in vitro (Martarelli et al., 2008), and in melanoma cells in vitro (Doudican N et al., 2008). A Phase I clinical trial reported by Morris et al.,2001 showed Albendazole, another Benzimidazole, had a high maximum tolerated dose when given to 36 patients with malignant tumors, 16% of which showed a decrease in tumor markers (Morris et al., 2001) . Fenbendazole is a benzimidazole drug commonly used for treating pinworm outbreaks in laboratory rodents (Coghlan et al., 1993). It has a wide margin of safety with an oral LD50 in mice of >10,000 mg/kg (O'Neil, 2001). This drug was shown to have a synergistic inhibition of lymphoma growth in SCID mice when combined in the diet with supplemental vitamins (Gao et al., 2008).However, a specific vitamin was not identified. There is evidence to suggest that vitamin E (RRR-α-tocopherol) may be beneficial in preventing or delaying PCa growth (Basu and Imrhan, 2005; Fleshner, 2002; Gronberg, 2003; Malafa et al., 2006). Vitamin E succinate (VES), the most potent derivative of vitamin E for anti-tumor activity (Basu and Imrhan, 2005), has been shown to induce apoptosis in PCa in vitro and in vivo through caspase-4 activation (Malafa et al., 2006). An in vitrostudy showed that when human PCa PC-3 cells were treated in culture with 20 μM of VES, there was a growth inhibition of 40% after 3 days of treatment (Zu and Ip, 2003). Especially when administered in the diet, VES has displayed chemopreventive effects (Basu and Imrhan, 2005). "

"FBZ+VES significantly inhibited growth of PCa cells and induced apoptosis in vitro. To our knowledge, this is the first time these drugs have been tested together in PCa cell lines."

"This synergistic ability of inhibition is very interesting, although the mechanisms involved is unclear. One hypothesis is that vitamin E activates multiple pro-apoptotic pathways such as targeting NF-κΒ (Ni and Yeh, 2007), and caspase-4 (Malafa et al., 2006), and if used with an agent that inhibits cell division such as one of the benzimidazoles, can be antagonistic to tumor growth."



Unexpected Antitumorigenic Effect of Fenbendazole when Combined with Supplementary Vitamins
Journal of the American Association for Laboratory Animal Science
Vol 47, No 6. November 2008

"The mice in this study had not been diagnosed with pinworms but were part of a facility treatment. Rodents in this area customarily were fed a commercial irradiated diet (Global 2918, Harlan Teklad, Madison, WI). However the equivalent treatment diet containing 150 ppm fenbendazole was available only in a sterilizable form (2018S, Harlan Teklad) supplemented with vitamins A, D, E, K, and B (Table 1) to compensate for loss during sterilization. Because the animal facility was not configured for dietary sterilization, the sterilizable diet was fed unautoclaved, with the result that mice received higher-than-normal concentrations of vitamins. Therefore the observed antitumor effect could have resulted from either the additional vitamins or the fenbendazole. Therefore a controlled study was conducted to test whether fenbendazole, supplemented vitamins, or both in combination affected the growth of this human lymphoma cell line in SCID mice."

"The mechanism for this synergy is as yet unknown. However, like other anticancer drugs such as taxanes, quinolones, and vinca alkaloids, fenbendazole inhibits microtubule polymerization. In addition, fenbendazole is a member of a large group of related anthelminthics, the benzimidazoles, and another member of this group, mebendazole, exerts antitumor effects by inhibition of tumor-induced neovascularization. However, in the present case, fenbendazole likely contributes to the antitumorigenic effect through its antimicrotubule activity.Supplemented vitamins included B, D, K, E, and A. Vitamins E and A both have antitumor properties by virtue of their antioxi-dant properties. Vitamin E causes antitumor and antimetastatic effects in several animal models of cancer; for example, it sup-presses the nuclear transcription factor NFκB in prostate cell lines."

 

[Rick K]

Another survivor, treated with Fenbendazole (animal deworming agent). Diagnosed with terminal small cell lung cancer August 2016.
Alive and well June 10 2021. Recent scan was an all clear NED ("no evidence of disease").

"The canine medicine that I took was available over the counter from numerous pet medicine on-line sites. It is branded as Panacur C and the drug name is Fenbendazole."

"You know, we've known for decades that these anthelmintic class of drugs (meaning to destroy parasites in the intestines) could have possible efficacy against cancer, and in fact in the 80's and 90's there was a drug called Levamisole that was used on colon cancer and it is an anthelmintic drug".

I said, "Doc, if you have known for decades why hasn't more work been done on it?" His answer was honest. He said, "probably because of money...all of these drugs are far off-patent and nobody is going to spend a gazillion dollars to repurpose them for cancer.....only to have generic competition the next day."

The website is a phenomenal resource and inspiration.

THE CONSOLIDATED STORY PUBLISHED AS ONE ENTRY FOR EASE OF USE ON MOBIL

AUGUST 2016 Attitude is Everything has always been my mantra. It seems that the more troublesome an event or challenge I've faced, my natural defense mechanism

www.mycancerstory.rocks

The biologist Hulda Clark has said for years: "kill the parasite and you cure the cancer". The parasite she's referring to is the sheep's liver fluke, a very common parasite.

 

[FredSonoma]

Interesting that Fenbendazole and Ivermectin are both anti-parasites