Can a low caloric diet or 5:2 one reverse NAFLD?

[mostlylurking]

nice.

I had to considerably up my caloric intake when megadosing niacinamide, to reduce weird feelings. And yes, niacin is bad; I learned that that's how Ray feels about it after I already tried it for a month, lol.

there's actually a thread about it, I'd suggest checking out:

B3 megadose for starch intolerance, IBS, and more.

I’m so stoked. I reversed some horrific reactions to starch via megadosing B3 (niacinamide), to fight fungal overgrowth (candida). Since I did 1.3 yrs of keto-carnivore, I became practically allergic to any starch, even after about 2 years of “peating.” Whether it was one beer (which I used to...

raypeatforum.com

Interesting thread at link you provided. But I've done a lot of reading/video watching about what thiamine does and I believe that it's the thiamine that is most essential for the health of the intestine. It has to do with "tight junction proteins". This also pertains to the integrity of the blood/brain barrier. Thiamine deficiency makes the bbb leaky too.

here's some info about it:

Dietary supplementation of thiamine enhances colonic integrity and modulates mucosal inflammation injury in goats challenged by lipopolysaccharide and low pH - PubMed

The current study aimed to investigate the protective effects of dietary thiamine supplementation on the regulation of colonic integrity and mucosal inflammation in goats fed a high-concentrate (HC) diet. Twenty-four Boer goats (live weight of 35·62 (sem 2·4) kg) were allocated to three groups...

pubmed.ncbi.nlm.nih.gov

Thiamine modulates intestinal morphological structure and microbiota under subacute ruminal acidosis induced by a high-concentrate diet in Saanen goats

Ruminant animals are generally fed with starch-rich grain as the main energy source, and the incidence of metabolic diseases such as subacute ruminal …

www.sciencedirect.com

Thiamin deficiency induces impaired fish gill immune responses, tight junction protein expression and antioxidant capacity: Roles of the NF-κB, TOR, p38 MAPK and Nrf2 signaling molecules - PubMed

In this study, we investigate the effects of dietary thiamin deficiency on immune responses, tight junctions, antioxidant capacity and related signaling molecules in the gills of young grass carp (Ctenopharyngodon idella). Fish were fed diets that contained 0.12-2.04 mg thiamin kg(-1) for 8...

pubmed.ncbi.nlm.nih.gov

Evidence for early blood-brain barrier breakdown in experimental thiamine deficiency in the mouse - PubMed

In order to assess the involvement of blood-brain barrier (BBB) breakdown in the pathogenesis of thiamine deficiency encephalopathy, autologous albumin immunohistochemistry was performed in mice which were rendered thiamine-deficient by pyrithiamine, a BBB-permeant antagonist of thiamine. In the...

pubmed.ncbi.nlm.nih.gov

Thiamine Deficiency - A Potential Cause of SIBO and other Gut Dysfunction?

Thiamine deficiency - A consequence or cause of SIBO? In the previous article, I explained how SIBO and gut dysbiosis could increase the risk of thiamine deficiency. Thiamine's uptake from the gut may be disrupted in cases of malabsorption, which is a common feature of SIBO. The composition of...

www.eonutrition.co.uk

 

[BRBsavinWorld]

Interesting thread at link you provided. But I've done a lot of reading/video watching about what thiamine does and I believe that it's the thiamine that is most essential for the health of the intestine. It has to do with "tight junction proteins". This also pertains to the integrity of the blood/brain barrier. Thiamine deficiency makes the bbb leaky too.

here's some info about it:

Dietary supplementation of thiamine enhances colonic integrity and modulates mucosal inflammation injury in goats challenged by lipopolysaccharide and low pH - PubMed

The current study aimed to investigate the protective effects of dietary thiamine supplementation on the regulation of colonic integrity and mucosal inflammation in goats fed a high-concentrate (HC) diet. Twenty-four Boer goats (live weight of 35·62 (sem 2·4) kg) were allocated to three groups...

pubmed.ncbi.nlm.nih.gov

Thiamine modulates intestinal morphological structure and microbiota under subacute ruminal acidosis induced by a high-concentrate diet in Saanen goats

Ruminant animals are generally fed with starch-rich grain as the main energy source, and the incidence of metabolic diseases such as subacute ruminal …

www.sciencedirect.com

Thiamin deficiency induces impaired fish gill immune responses, tight junction protein expression and antioxidant capacity: Roles of the NF-κB, TOR, p38 MAPK and Nrf2 signaling molecules - PubMed

In this study, we investigate the effects of dietary thiamin deficiency on immune responses, tight junctions, antioxidant capacity and related signaling molecules in the gills of young grass carp (Ctenopharyngodon idella). Fish were fed diets that contained 0.12-2.04 mg thiamin kg(-1) for 8...

pubmed.ncbi.nlm.nih.gov

Evidence for early blood-brain barrier breakdown in experimental thiamine deficiency in the mouse - PubMed

In order to assess the involvement of blood-brain barrier (BBB) breakdown in the pathogenesis of thiamine deficiency encephalopathy, autologous albumin immunohistochemistry was performed in mice which were rendered thiamine-deficient by pyrithiamine, a BBB-permeant antagonist of thiamine. In the...

pubmed.ncbi.nlm.nih.gov

Thiamine Deficiency - A Potential Cause of SIBO and other Gut Dysfunction?

Thiamine deficiency - A consequence or cause of SIBO? In the previous article, I explained how SIBO and gut dysbiosis could increase the risk of thiamine deficiency. Thiamine's uptake from the gut may be disrupted in cases of malabsorption, which is a common feature of SIBO. The composition of...

www.eonutrition.co.uk

I agree of course, I’ve megadosed thiamine for a 3 month span, and continue to take high doses of it daily for about a year, but niacinamide just did something in a short timeframe for starch digestion at least, that B1 didn’t. Idk what’s different.

 

[mostlylurking]

I agree of course, I’ve megadosed thiamine for a 3 month span, and continue to take high doses of it daily for about a year, but niacinamide just did something in a short timeframe for starch digestion at least, that B1 didn’t. Idk what’s different.

What did the niacinamide do for the starch digestion? I know that starch breaks down to straight glucose which requires thiamine as a cofactor for three different enzymes in order to make ATP out of it. I don't know where niacinamide would fit in other than resolving the stress created by the high insulin created by the starch which turns to straight glucose. Niacinamide helped me a lot and facilitated weight loss but I always interpreted this as this being from niacinamide keeping the free fatty acids low so the cells could burn glucose and also by it improving the nad/nadh ratio (it's used to turn nadh back to nad).

 

[BRBsavinWorld]

What did the niacinamide do for the starch digestion? I know that starch breaks down to straight glucose which requires thiamine as a cofactor for three different enzymes in order to make ATP out of it. I don't know where niacinamide would fit in other than resolving the stress created by the high insulin created by the starch which turns to straight glucose. Niacinamide helped me a lot and facilitated weight loss but I always interpreted this as this being from niacinamide keeping the free fatty acids low so the cells could burn glucose and also by it improving the nad/nadh ratio (it's used to turn nadh back to nad).

Hmm, IDK, but I read that B3 basically helped strengthen the gut wall; I wonder if it's helpful in tandem with B1. I don't have any ideas about the actual mechanism.

I know I went into it trying to cure fungal overgrowth, but I still have fungal symptoms, yet can still eat starch.

 

[mostlylurking]

Hmm, IDK, but I read that B3 basically helped strengthen the gut wall; I wonder if it's helpful in tandem with B1. I don't have any ideas about the actual mechanism.

I know I went into it trying to cure fungal overgrowth, but I still have fungal symptoms, yet can still eat starch.

Ray Peat, PhD Quotes on Therapeutic Effects of Niacinamide – Functional Performance Systems (FPS)

About the starch:

Ray Peat, PhD – Concerns with Starches – Functional Performance Systems (FPS)

 

[SamYo123]

Ray Peat, PhD Quotes on Therapeutic Effects of Niacinamide – Functional Performance Systems (FPS)

About the starch:

Ray Peat, PhD – Concerns with Starches – Functional Performance Systems (FPS)

Well peat now eats rice again.... Ray Peat Interview - Dr Ray Peat - Blood Tests, Hormones, Protein Intake, & Ray's Carb List - Jodellefit