I was reading on DHEA from Wikipedia and was surprised to read that calorie restriction increased DHEA (http://www.sciencedirect.com/science/ar ... 6502001468).
RP talks about DHEA as a youth hormone, decreasing with age. Yet, those animals on calorie restriction that show suppressed metabolism ("decreased body temperature" and other cited symptoms), their DHEA is increased. This is used in other studies as an argument to explain why calorie restriction improve life span. If I hadn't read RP, I would have concluded: slow metabolism -> increased DHEA -> longer life span.
What am I getting wrong?
RP talks about DHEA as a youth hormone, decreasing with age. Yet, those animals on calorie restriction that show suppressed metabolism ("decreased body temperature" and other cited symptoms), their DHEA is increased. This is used in other studies as an argument to explain why calorie restriction improve life span. If I hadn't read RP, I would have concluded: slow metabolism -> increased DHEA -> longer life span.
What am I getting wrong?