Calcium Deficiency Increases Aromatase And Subsequent Estrogen In Male Rats

[Lokzo]

A calcium-deficient diet caused decreased bone mineral density and secondary elevation of estrogen in aged male rats-effect of menatetrenone and elcatonin.


@haidut You will like this :)

 

[ecstatichamster]

Nice find thanks.

 

[Lokzo]

Nice find thanks.

I was as excited as you are! Haha.
Thanks. Love researching.

 

[tankasnowgod]

A calcium-deficient diet caused decreased bone mineral density and secondary elevation of estrogen in aged male rats-effect of menatetrenone and elcatonin.


@haidut You will like this :)

Pretty interesting. Vitamin K2 also looks really good in the study, preserving bone mass on the CA deficient diet, and lowering high estrogen. Yet the dose they used was huge (30mg/kg bodyweight a day, meaning more than 350 mg a day for a 75kg human), and still, the hormonal profile wasn't as good as rats on the "regular" diet.

PTH and Activated Vitamin D was also higher in the K2 group than the Regular diet group, or just the CA deficient rats-

Not ideal, but I guess dealing with higher levels of stress hormones is better than having weaker bones. Of course, as free living humans, no reason you can't eat higher calcium AND supplement K2. You'd likely get the benefits of both, and wouldn't have to slam down 100s of mg of K2 a day. That could get pricey quick.

Also, look how serum calcium is higher on the calcium deficient diets! I guess this is also good evidence of the "calcium paradox" that Peat writes about in this article-

Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy

Ray Peat

raypeat.com