Calcium Channel Blockade By Magnesium Chloride On Memory. Dementia


Jul 8, 2016
I don't fully understand this one myself, it looks interesting though and have seen calcium channel blockers mentioned before on here. The study concludes that this should be considered when designing treatment for dementia and other memoryproblems.

Sex- and dose-dependent effects of post-trial calcium channel blockade by magnesium chloride on memory for inhibitory avoidance conditioning - ScienceDirect

Sex- and dose-dependent effects of post-trial calcium channel blockade by magnesium chloride on memory for inhibitory avoidance conditioning
Lynda A. Wilmott. Lucien T. Thompson.
The University of Texas at Dallas, Cognition & Neuroscience Program, School of Behavioral & Brain Sciences, 800 West Campbell Road, GR4.1, Richardson, TX 75080, USA
Sex- and dose-dependent effects of post-trial calcium channel blockade by magnesium chloride on memory for inhibitory avoidance conditioning - ScienceDirect

Memory for aversive inhibitory avoidance (IA) conditioning is affected by Ca2+ influx.

MgCl2 dose-dependently enhanced memory for inhibitory avoidance conditioning.

MgCl2 enhanced long-term memory at a lower dose in males than females."

"In our study, magnesium chloride dose-dependently enhanced memory compared to controls (significantly increased latency to enter a dark compartment previously paired with an aversive stimulus) when tested 48 h later as compared to controls. A leftward shift in the dose response curve for memory enhancement by magnesium chloride was observed for male compared to female rats. These findings provide further insights into calcium-dependent modulation of aversive memory, and should be considered when assessing the design of effective treatment options for both male and female patients with dementia or other memory problems."
Similar threads
Thread starter Title Forum Replies Date
D Seeking Calcium Channel Blockers For 5G Pharmaceutical Drugs 3
Cirion Voltage Gate Calcium Channel & EMF's & Dairy Intake? Calcium 12
cellboy Which Calcium Channel Blockers Are Recommended Around Here? Supplements, Pharmaceutical Drugs 4
J Calcium Channel Blocker Rejuvenates Dopaminergic Neurons Scientific Studies 11
haidut Androgens (androsterone/DHEA/T) Are Calcium Channel Blockers / Antagonists Scientific Studies 9
M Addressing Hair Loss and High Calcium Intake Hair & Nails 7
youngsinatra Can High Vitamin D Compensate Lower Dietary Calcium? Ask For Help or Advice 4
C Calcium and atherosclerosis Supplements 1
GelatinGoblin Which milk has the best Phosphorus to Calcium ratio? Dairy 29
J Eggshell as calcium acetate Eggs 3
M High calcium ? Ask For Help or Advice 0
RWilly A cautionary note for those drinking milk and using baking soda or calcium carbonate Milk 3
M How to find out if there’s too much calcium in my body? Ask For Help or Advice 3
S How much calcium is too little? Diet 9
RWilly Baking Powder - a surprising amount of calcium - high calcium to phosphorus ratio Miscellaneous Health Discussions 6
A Calcium supplementation Diet 12
J Am I good to eat red meat with H63D gene as long as i donate blood, eat iron rich foods with calcium Minerals 0
md_a Elevation of intracellular calcium - Hair Loss Scientific Studies 1
S Thoughts on this sea calcium supplement? Ask For Help or Advice 1
Hgreen56 Does milk or calcium raise gaba? Milk 3
Jam Mortality From Coronavirus Disease 2019 Increases With Unsaturated Fat and May Be Reduced by Early Calcium and Albumin Supplementation Miscellaneous Health Discussions 3
R Milk for LPR (silent reflux)? Calcium? Milk 10
J Calcium and self harm Ask For Help or Advice 3
N Do you need extra calcium with high dose k2? K 16
V Strong improvement in chronic fatigue after eggshell calcium Calcium 15
S Dark urine from Calcium Carbonate? Ask For Help or Advice 0
M Supplement Calcium when PTH is low? Calcium 8
deliciousfruit pharmacist says to take thyroid on an empty stomach, and avoid calcium for 4 hours Supplements, Pharmaceutical Drugs 3
Bogdar Low PTH, Low D, High Calcium - How Is It Possible? Blood Work, Labs 16
Velve921 Calcium Supplementation Supplements 4
G Calcium-Phosphorus Ratio In Animal Protein Sources: What To Choose? Diet 7
S Best Non Dairy And Non Supplement Ways To Get Calcium? Digestion 18
haidut PUFA Exacerbate, Saturated Fats (SFA) / Albumin / Calcium Ameliorate COVID-19 Scientific Studies 2
S Hypoparathyroid And High Blood Calcium? Blood Work, Labs 4
D Calcium Carbonate (Eggshell Calcium) Causes Flat Stools? Ask For Help or Advice 1
M Percentage Of Glycine In Chelated Calcium Ask For Help or Advice 1
Julian Calcium Sulfate Supplements, Pharmaceutical Drugs 5
L What Causes/How To Heal Calcium Disregulation? Metabolism 13
N Bad Reaction To Traditional Food Market Whole Bone Calcium Supplement Diet 6
Ben Stone Calcium In Excess Of Seawater Ratio Dangerous Ray Peat Topics 28
BearWithMe My Body Doesn't Metabolise Calcium Properly And Nothing Seems To Help Ask For Help or Advice 45
L What Raises/Lowers Serum Calcium? Metabolism 4
J Calcium Hydroxyapatite/MCHA A Superior Form Of Calcium Minerals 3
J How To Reduce The Constipation Effect From Calcium Supplements Calcium 5
L Calcium Acetate From Eggshell Powder Supplements, Pharmaceutical Drugs 2
wealthofwisdom Non-Milk Calcium Sources? Diet 14
Tristan Loscha Monocyte Mitochondrial Function In Calcium Oxalate Stone Formers Vegetables, Grains, Legumes, Fiber 1
A Calcium Alpha-ketoglutarate. A Calcium Supplement With Added Benefits? Calcium 31
J The Best Calcium Supplement Calcium 3

Similar threads