Caffeine Improving Sugar Handling And Fat Accumulation In Rats

Dan W

Member
Joined
Jan 22, 2013
Messages
1,528
I finally managed to post a study before Haidut's high-powered laser-guided tracking system could beat me to it.

Caffeine Restores Insulin Sensitivity and Glucose tolerance in High-sucrose Diet Rats: Effects on Adipose Tissue
Chronic caffeine administration improved whole-body glucose homeostasis and insulin signaling pathways in adipose tissue in [high sucrose] animals in a concentration dependent manner.
We also concluded that chronic caffeine administration avoids visceral and total fat accumulation in a concentration dependent manner in [high sucrose] animals, without altering animal’s body weight. Although caffeine did not directly affect [insulin receptor] expression in the adipose tissue, it stimulates the insulin signaling cascade. Therefore, we can suggest that this may be one of the mechanisms for caffeine-induced improvement of insulin sensitivity in [high sucrose] rats.

The concentrations necessary might not be as high as they sound initially. This discussion on SuppVersity suggests ~16 mg/kg in humans after accounting for Wistar rats and their lack of drinkin' much.
 

milk_lover

Member
Joined
Aug 15, 2015
Messages
1,909
Coffee for the win! Thanks Dan. So adding a lot of white sugar in coffee seems pretty safe after all :)
 

Similar threads

Back
Top Bottom