Caffeine can be used to manage IBS / IBD and Chron's

haidut

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I know people with IBS who swear by their morning coffee and cigarette. I am not encouraging smoking of course.

http://www.ncbi.nlm.nih.gov/pubmed/23925589

"...Development of acute colitis is reduced upon caffeine treatment. The mechanism involves the down-regulation of CHI3L1 expression and its associated bacterial interaction effect. Therefore, caffeine is proposed as a safe and economical candidate for successful IBD management."
 

Suikerbuik

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http://en.wikipedia.org/wiki/CHI3L1

Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40. The exact physiological role of YKL-40 is not known, but it has been implicated in development, inflammatory disease (such as asthma,[4] and cancer progression). YKL-40 is a Th2 promoting cytokine that is present at high levels in the tumor micro-environment and in the serum of cancer patients.
 

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