Bile Acid Stimulates Mitochondrial Function, Could Treat Parkinson And Alzheimer's

[ddjd]

Should be fine. Taurine/glycine also stimulate bile production as @Joeyd mentioned. I think thyroid does too.

how much taurine/glycine do you think would be effective for increasing bile production?

 

[aliml]

Bile acids profile in Parkinson’s disease​

We demonstrated a significant elevation of liver-derived primary bile acid Cholic Acid (CA), and bacterially generated secondary bile acid Deoxycholic Acid (DCA) as well as conjugated bile acid Taurodeoxycholic Acid (TDCA), Glycodeoxycholic Acid (GDCA), Glycodeoxycholic acid 3-Sulfate (GDCS), Taurocholic Acid 3-Sulfate (TCAS) and Glycolithocholic Acid 3-Sulfate (GLCAS) in Parkinson’s disease compared to Healthy control.

Interestingly, Ursodeoxycholic Acid (UDCA) and Tauroursodeoxycholic Acid (TUDCA), which were reported neuroprotective in Parkinson’s disease, were decreased in the plasma of Parkinson’s patients.

Comprehensive metabolic profiling of Parkinson’s disease by liquid chromatography-mass spectrometry

Parkinson’s disease (PD) is a prevalent neurological disease in the elderly with increasing morbidity and mortality. Despite enormous efforts, rapid and accurate diagnosis of PD is still compromised. Metabolomics defines the final readout of genome-environment ...

www.ncbi.nlm.nih.gov

 

[Grapelander]

2006: Synthetic Bile acids for AIDS
A family of compounds called Ceragenins (or CSAs), mimics the disease-fighting characteristics of anti-microbial and anti-viral agents produced naturally by a healthy human immune system. What studies to date show is a compound that attacks HIV at its molecular membrane level, disrupting the virus from interacting with their primary targets, the "T-helper" class white blood cells that comprise and direct the human immune system. Further, CSAs appear to be deadly to all known strains of HIV.

Ceragenins (cationic steroid compounds), a novel class of antimicrobial agents
Ceragenins are a group of cholic acid derivatives that have been chemically modified to make them cationic amphiphiles. Several of these derivatives exhibit antimicrobial activity against a broad range of bacteria.