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DHT often gets shuttled to areas of high estrogenic activity to control cellular proliferation caused by estrogen and estrogenic metabolites. Same thing happens in breast in prostate cancer - these patients have high DHT levels in breast and prostate but it is there to control estrogen when progesterone is low or not available at all. The 5-androstenediol is a potent estrogen, and a much potent estrogen than it is an androgen. So, a build up of 5-androstenediol will also tend to cause local accumulation of DHT to control the damage and thus DHT gets the blame.
Interesting ; I see a lot of fat people with very good looking beard do you think dht could be involved here as a defensive mechanism? To a certain extent wouldn)'t the body try to increase dht (since it's the most potent androgen) in tissues to counter the effects of too much estrogens? But afaik dht levels are inversely correlated with belly fat, maybe it's again a question of tissue levels vs blood levels.
Something like sorghum shows signs of increasing 5-ar activity and yet it increases hair loss a whole lot. To be fair I saw cyanide, nitrate and iron could be present in decent amounts in sorghum depending on how it's grown (Cyanide (prussic acid) and nitrate in sorghum crops), so despite potentially increasing 5-ar, containing b3 and magnesium in good amounts , it's pretty awful.
I would love to see the chemicals which increase 5-ar activity isolated.
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