Best Anti-aging/reverse Senescence Regimens/methods Today?

[baccheion]

Keep the rate of dermal collagen loss low. Same with bone density loss. If caught/started young, minimal aging while none being lost.

An extended fast..

Some said a cycle of hGH restored their skin/collagen. Maybe megadose vitamin B3 at night and/or alpha-GPC (vitamin B4) in the AM on an empty stomach will have a similar effect.

Blocking the need to suck up collagen and bone limits the loss. Megadose vitamin D3 is said to also slow loss.

Melatonin seeps even into mitochondria and quenches inflammation + free radicals. I believe it also works on lipofuscin. Decline with age may be a part of the degradation mechanism.

Then vitamins, especially C and fat-solubles, and minerals. MSM lotion.

Many don't meet all RDAs and get enough quality sleep..

 

[Motorneuron]

Increasing metabolism a la peat will inevitably and undoubtedly result in more rapid aging. This is basically the very reason that the entire scientific community turned away from high metabolism. Some. Scientist a hundred years ago put some bacteria or fungi in a petri dish, heated them up and saw them replicate/die faster, then he did the same but applied ice under the dish and saw the process slow down, and came to the possibly correct conclusion that heat bad/cold good and the rest is history.

It's a question of quality vs quantity. If you want to live well you need high testosterone, high thyroid, a body that's hot to the touch, high energy levels... All of which are known to lower lifespan. Do you want 85 years of medium to low-quality life or 65 years of high-quality life?

Many, at least in recent months, agree that reductive stress (therefore low metabolism) creates more damage than the oxidized state (high metabolism) ... you are saying the opposite, right?

 

[baccheion]

Many, at least in recent months, agree that reductive stress (therefore low metabolism) creates more damage than the oxidized state (high metabolism) ... you are saying the opposite, right?

Is it not fine when also slightly calorie restricted (even less than 10%)?

 

[JamesGatz]

So whats the logic that high metabolism is bad for negligible senescence ? Every negligible senescent species lives in the wild in a healthy metabolic environment and they don't age

Animals under stress (such as in zoos or in the wild but on carnivore) age REALLY BADLY - sounds like BRO SCIENCE