https://www.gastrojournal.org/article/S0016-5085(02)29245-8/pdf
In this study the authors assessed not only the type but the quantity of the bacteria present adhering to the intestinal surface in healthy controls and people with UC and Chrons disease. What they found is copied and pasted below. Check out the study though, the researchers actually photographed the microscopic pictures showing the bacterial colonies adhered to the patients intestinal wall.
“Using a simple and reliable protocol of biopsy wash followed by hypotonic lysis, we showed that the mucosal surface in healthy controls is basically sterile and that the concentrations of mucosal bacteria increased progressively from self-limiting colitis to indeterminate colitis to IBD, being highest in CD patients.”
“Similar to previous studies, we found no principal difference in the composition of the mucosal flora in IBD patients and controls.4,15–17 Species isolated from the washed mucosa were of fecal origin in all groups.”
“We hypothesize that the healthy mucosa is capable of holding back fecal bacteria, preventing a close contact of resident microflora with the epithelial surface. This mucosal cleaving function is disturbed in patients with IBD primary to local inflammatory changes.“
In this study the authors assessed not only the type but the quantity of the bacteria present adhering to the intestinal surface in healthy controls and people with UC and Chrons disease. What they found is copied and pasted below. Check out the study though, the researchers actually photographed the microscopic pictures showing the bacterial colonies adhered to the patients intestinal wall.
“Using a simple and reliable protocol of biopsy wash followed by hypotonic lysis, we showed that the mucosal surface in healthy controls is basically sterile and that the concentrations of mucosal bacteria increased progressively from self-limiting colitis to indeterminate colitis to IBD, being highest in CD patients.”
“Similar to previous studies, we found no principal difference in the composition of the mucosal flora in IBD patients and controls.4,15–17 Species isolated from the washed mucosa were of fecal origin in all groups.”
“We hypothesize that the healthy mucosa is capable of holding back fecal bacteria, preventing a close contact of resident microflora with the epithelial surface. This mucosal cleaving function is disturbed in patients with IBD primary to local inflammatory changes.“
