B3 and Insulin resistance

[Highserotonin90]

I find this study:

B3 Does Insulin Resistance Worsen?

@haidut @Hans

Thanks

 

[Kvothe]

I find this study:

B3 Does Insulin Resistance Worsen?

@haidut @Hans

Thanks

I think so not.

 

[Hans]

I find this study:

B3 Does Insulin Resistance Worsen?

@haidut @Hans

Thanks

Niacin might, niacinamide doesn't.

 

[freedom]

Niacin might, niacinamide doesn't.

Why would niacinamide not increase the chances of insulin resistance? From this study both raised triglycerides and the amount taken would be a variable that would need to be tested:

Niacin (B3) & Glucose Management | Part V of the "There is More To Glucose Control Than Carbohydrates"-Series. Plus: Can You Use Niacin to Ramp Up Fat Burning During Fasts?

Some scientists speculate that niacin could be the root cause of the diabesity epidemic. Others believe that it's the solution. Today's SuppVersity article will let both groups have their say so that you can decide, whether you'd better avoid or consume niacin fortified foods and / or...

suppversity.blogspot.com

 

[Kvothe]

Why would niacinamide not increase the chances of insulin resistance? From this study both raised triglycerides and the amount taken would be a variable that would need to be tested:

View attachment 22570

Niacin (B3) & Glucose Management | Part V of the "There is More To Glucose Control Than Carbohydrates"-Series. Plus: Can You Use Niacin to Ramp Up Fat Burning During Fasts?

Some scientists speculate that niacin could be the root cause of the diabesity epidemic. Others believe that it's the solution. Today's SuppVersity article will let both groups have their say so that you can decide, whether you'd better avoid or consume niacin fortified foods and / or...

suppversity.blogspot.com

Why should triglycerides lead to IR? Also, the graph clearly shows that HOMA is going down as the dose of NAM increases.

 

[freedom]

Yes, lowering HOMA is very good but what trigs are being raised? If your saturated fat and carnitine levels are high that should also mean that levels of niacinamide in the cell need to be high enough to avoid an excess of NADH. So a high NAD/NADH ratio may be mandatory to prevent the IR caused by high beta-oxidation of saturated fat in the mitochondria. There are a number of variables that come into play and high protein or meat diet would increase carnitine (needed to shuttle saturated fat into the mitochondria):

Carnitine: a controversial view and why it can actually be bad for you » TESTONATION

Is carnitine good for you because it boosts fat oxidation or is it because of something else? Read to find out why carnitine is actually helpful.

men-elite.com

 

[mrchibbs]

Yes, lowering HOMA is very good but what trigs are being raised? If your saturated fat and carnitine levels are high that should also mean that levels of niacinamide in the cell need to be high enough to avoid an excess of NADH. So a high NAD/NADH ratio may be mandatory to prevent the IR caused by high beta-oxidation of saturated fat in the mitochondria. There are a number of variables that come into play and high protein or meat diet would increase carnitine (needed to shuttle saturated fat into the mitochondria):

Carnitine: a controversial view and why it can actually be bad for you » TESTONATION

Is carnitine good for you because it boosts fat oxidation or is it because of something else? Read to find out why carnitine is actually helpful.

men-elite.com

Are trigs inherently bad though? Ray has said that they are saturated lipid made in the liver from excess sugar, I think they're just a storage form of energy.