Mauritio
Member
- Joined
- Feb 26, 2018
- Messages
- 5,669
B. Coagulans , a spore forming bacteria, few people proably have heard of . In my opinion it's one of the best probiotics and bacteria strains available.
It decreases endotoxin ,liver fibrosis inflammation, boosts a very healthy bacterium called F. Prausnitzii, which in turn lowers serotonin and produces butyrate and salicylic acid .
B. Coagulans also helps people with Crohns and IBS ,as it has been shown that its count is ver lowni nthise people.
1. This study shows in mice fed a high cholesterol diet B. coagulans was able to lower liver weight + enzymes , cholesterol and LDL .
2 . This study shows that B. Coagulans increases F. Prausnitzii. A very beneficial bacterium for the following reason:
- it decreases serotonin:
"Importantly, mice treated with either F. prausnitzii or its SN exhibited significant decreases in intestinal permeability, tissue cytokines and serotonin levels."
(Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model)
- it increases butyrate and consumes acetate, another study found a synergistic between B.Coagulans and vinegar ,which contains acetate :
"F. prausnitzii is an acetate-consuming and butyrate-producing bacterium [27, 16]. Although it is one of the most common bacteria found in the human colon, it has been revealed that F. prausnitzii needs the presence of B. thetaiotamicron, a primary acetate-producer, in order to colonize the colon [27].
- it doesn't haveb lps on the outer membrane so it doesnt activat TLR4 :
"LPS proteins are ligands for the transmembrane protein, TLR4 (Toll-like receptor 4). These are not found on F. prausnitzii or other bacteria in clostridial cluster IV. This suggests that F. prausnitzii is one of the unique bacteria whose dermis structure does not necessarily align with its Gram-stain [17]."
- That B. Coagulans increases F. Prausnitzii is special since theres no commercial probiotic that contains it so far . So B. Coagulans and Vitmain B2 are probably your best bet to increase it .
- F. Prausnitzii produced salicylic acid in the gut ,which has anti-microbial properties of its own.
(Faecalibacterium prausnitzii treatment improves hepatic health and reduces adipose tissue inflammation in high-fat fed mice)
3. B. Coagulans is effective on it's own but this study shows that combined with ACV (Apple cider vinegar) it was even more effective. if theres more acetate from vinegar F. Prausnitzii can increase more easily , so I would guess it's from that .
B. coagulans, reduced food intake, attenuated body weight gain and enhanced glucose tolerance, only the supplemented drink improved the lipid serum profile and prevented hepatic HFD-induced overexpression of CD36, IL-1β, IL-6, LXR and SREBP, thus reducing lipid deposition in the liver. The beneficial properties of the B. coagulans-supplemented vinegar appear to be mediated by a reduction in insulin and leptin circulating levels.
(A Combination of Apple Vinegar Drink with Bacillus coagulans Ameliorates High Fat Diet-Induced Body Weight Gain, Insulin Resistance and Hepatic Steatosis - PubMed)
4. B. Coagulans also increases B. spp ,which is one of the few bacteria that don't produce serotonin. I talked about it a little in this thread.
It decreases endotoxin ,liver fibrosis inflammation, boosts a very healthy bacterium called F. Prausnitzii, which in turn lowers serotonin and produces butyrate and salicylic acid .
B. Coagulans also helps people with Crohns and IBS ,as it has been shown that its count is ver lowni nthise people.
1. This study shows in mice fed a high cholesterol diet B. coagulans was able to lower liver weight + enzymes , cholesterol and LDL .
Effect of Probiotics Bacillus coagulans and Lactobacillus plantarum on Lipid Profile and Feces Bacteria of Rats Fed Cholesterol-Enriched Diet - PubMed
The aim of this study was to investigate the effect of Lactobacillus plantarum and Bacillus coagulans on serum lipid profile and lowering potential of probiotic in hypercholesterolemic rats. Twenty-eight male Wistar rats were divided into four groups as follows: (1) control group, fed standard...
pubmed.ncbi.nlm.nih.gov
2 . This study shows that B. Coagulans increases F. Prausnitzii. A very beneficial bacterium for the following reason:
- it decreases serotonin:
"Importantly, mice treated with either F. prausnitzii or its SN exhibited significant decreases in intestinal permeability, tissue cytokines and serotonin levels."
(Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model)
- it increases butyrate and consumes acetate, another study found a synergistic between B.Coagulans and vinegar ,which contains acetate :
"F. prausnitzii is an acetate-consuming and butyrate-producing bacterium [27, 16]. Although it is one of the most common bacteria found in the human colon, it has been revealed that F. prausnitzii needs the presence of B. thetaiotamicron, a primary acetate-producer, in order to colonize the colon [27].
- it doesn't haveb lps on the outer membrane so it doesnt activat TLR4 :
"LPS proteins are ligands for the transmembrane protein, TLR4 (Toll-like receptor 4). These are not found on F. prausnitzii or other bacteria in clostridial cluster IV. This suggests that F. prausnitzii is one of the unique bacteria whose dermis structure does not necessarily align with its Gram-stain [17]."
Faecalibacterium prausnitzii - microbewiki
microbewiki.kenyon.edu
- That B. Coagulans increases F. Prausnitzii is special since theres no commercial probiotic that contains it so far . So B. Coagulans and Vitmain B2 are probably your best bet to increase it .
- F. Prausnitzii produced salicylic acid in the gut ,which has anti-microbial properties of its own.
(Faecalibacterium prausnitzii treatment improves hepatic health and reduces adipose tissue inflammation in high-fat fed mice)
3. B. Coagulans is effective on it's own but this study shows that combined with ACV (Apple cider vinegar) it was even more effective. if theres more acetate from vinegar F. Prausnitzii can increase more easily , so I would guess it's from that .
B. coagulans, reduced food intake, attenuated body weight gain and enhanced glucose tolerance, only the supplemented drink improved the lipid serum profile and prevented hepatic HFD-induced overexpression of CD36, IL-1β, IL-6, LXR and SREBP, thus reducing lipid deposition in the liver. The beneficial properties of the B. coagulans-supplemented vinegar appear to be mediated by a reduction in insulin and leptin circulating levels.
(A Combination of Apple Vinegar Drink with Bacillus coagulans Ameliorates High Fat Diet-Induced Body Weight Gain, Insulin Resistance and Hepatic Steatosis - PubMed)
4. B. Coagulans also increases B. spp ,which is one of the few bacteria that don't produce serotonin. I talked about it a little in this thread.
Last edited: