Autism caused by low allopregnenolone , chinese herb can treat

[Mauritio]

Best supplements to raise allopregnanolone?

progesterone, pregnenolone, 5aDHP, anything else?

The herbal formula that this thread is about seems very convincing .

 

[Mauritio]

Here's a study showing that it increases allopregnanolone.

"The level of allopregnanolone was increased by administration of FEWP. In summary, this study indicated that the anti-PTSD effects of FEWP were associated with allopregnanolone biosynthesis."

Free and Easy Wanderer Plus (FEWP) improves behavioral deficits in an animal model of post-traumatic stress disorder by stimulating allopregnanolone biosynthesis

Post-traumatic stress disorder (PTSD) is a severe psychiatric condition defined as a “trauma and stress-related disorder”. Dampened allopregnanolone b…

www.sciencedirect.com

 

[golder]

potentially induced liver injury here? Although haven’t analysed the details of the study:

Liver Injury Induced by the Japanese Herbal Drug Kamishoyosan – Gastroenterology & Hepatology

www.gastroenterologyandhepatology.net

 

[Mauritio]

potentially induced liver injury here? Although haven’t analysed the details of the study:

Liver Injury Induced by the Japanese Herbal Drug Kamishoyosan – Gastroenterology & Hepatology

www.gastroenterologyandhepatology.net

That's just a case report. And it doesn't even make sense, so you can't conclude anything from it .
She had menopause problems ,which equals high estrogen and then they're wondering why the liver enzymes are high ...

Plus I've posted an in vivo study showing that this formula actually inhibited liver fibrosis, so I wouldn't take this case report too serious .

 

[GenericName86]

For those using or who have tried Kami-shoyo-san/Jia Wei Xiao Yao Pian where did you source it from? Really interested in giving it a try but unsure of a good vendor.

 

[Mauritio]

For those using or who have tried Kami-shoyo-san/Jia Wei Xiao Yao Pian where did you source it from? Really interested in giving it a try but unsure of a good vendor.

Activeherb seems legit they have a lot of good reviews and claim to use as few fillers as possible :)

 

[GenericName86]

Activeherb seems legit they have a lot of good reviews and claim to use as few fillers as possible :)

Thanks!

 

[Mauritio]

Kami shoyo san increased the 5ht1a receptor expression and increases BDNF .
I'm still not sure how good that is but its probably the best serotonin receptor to activate as it increases dopamine and decreases serotonin. But wikipedia says 5ht1a also increases various stress hormones .
The increase in BDNF is great for brain health no matter what.


The same study also shows a decrease in cortisol under chronic stress !

Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice - PubMed

Females are well known to suffer disproportionately more than males from stress-related neuropsychiatric disorders, especially during perimenopausal and postmenopausal periods. In addition to a decline in serum estradiol levels, environmental stress and social stress likely contribute to the...

pubmed.ncbi.nlm.nih.gov

 

[Sospian]

It also inhibits liver fibrosis and lipid peroxidation.

A Chinese herbal medicine, jia-wei-xiao-yao-san, prevents dimethylnitrosamine-induced hepatic fibrosis in rats - PubMed

Jia-wei-xiao-yao-san (JWXYS) is a traditional Chinese herbal medicine that is widely used to treat neuropsychological disorders. Only a few of the hepatoprotective effects of JWXYS have been studied. The aim of this study was to investigate the hepatoprotective effects of JWXYS on...

pubmed.ncbi.nlm.nih.gov

Jia Wei Xiao Yao Pian = Jai Wei Xiao Yao San?

Ebay is giving me lots of different results:

Jia Wei Xiao Yao
Jia Wei Xiao Yao Pian Wan
Jia Wei Xiao Yao Wan Pian San

I'm assuming they're adding different herbs but not knowing exactly what you're taking can be a bit unsettling

 

[Mauritio]

Jia Wei Xiao Yao Pian = Jai Wei Xiao Yao San?

San or Pian is just the difference between powder and pill AFAIK . So the same substance .

 

[sugarisgreat]

?

The alphabetical list on the right hand side has several articles for pregnenlogne. I was thinking it was the same thing.

 

[Mauritio]

Another confirmation that it increases allopregnanolone.

The role of allopregnanolone in the anxiolytic-like effect of free and easy wanderer plus (FEWP), a polyherbal preparation - PubMed

Anxiety disorders are the serious and burdensome psychiatric illnesses, which are closely correlated with allopregnanolone. The down-regulation of allopregnanolone biosynthesis has been implicated as the possible contributor to the aetiology of anxiety disorders. Free and easy wanderer plus...

pubmed.ncbi.nlm.nih.gov

 

[Ismail]

I ordered it ?

Which brand did you order?

 

[Ismail]

Another confirmation that it increases allopregnanolone.

The role of allopregnanolone in the anxiolytic-like effect of free and easy wanderer plus (FEWP), a polyherbal preparation - PubMed

Anxiety disorders are the serious and burdensome psychiatric illnesses, which are closely correlated with allopregnanolone. The down-regulation of allopregnanolone biosynthesis has been implicated as the possible contributor to the aetiology of anxiety disorders. Free and easy wanderer plus...

pubmed.ncbi.nlm.nih.gov

Hey buddy, you just replied to my message in the other post about what raises allopregnanolone, what benefits are you experiencing already from this herbal mixture? Thanks again.

 

[Mauritio]

Hey buddy, you just replied to my message in the other post about what raises allopregnanolone, what benefits are you experiencing already from this herbal mixture? Thanks again.

My brain seems to work differently . Almost like its re-wirering. I feel more creative and want do and get things in order. Less interest in social media and things that I did because they gave me a small dopamin spike .
I think I'm doing more things that make long term sense .
I also feel a sense of appreciation and sometimes even happiness that is totally different from the feeling that dopaminergic drugs give you . It's only day 3 so take it with a grain of salt .

Plus the first 2 days I had diarrhea . So it's definitely doing something down there , I have chronic gut problems, so I'm sure it's detoxing something.
This mix is also prescribed for gut problems so it is normal to some degree .

 

[Mauritio]

Which brand did you order?

Jia Wei Xiao Yao San

加味逍遙散 (Jia Wei Xiao Yao San) Verstärktes Pulver der heiteren Ungebundenheit (Dan Zhi Xiao Yao San) Erhältlich als: 84 Tabletten à ca. 500 mg 42g netto…

www.phytocomm.lu

 

[Ismail]

My brain seems to work differently . Almost like its re-wirering. I feel more creative and want do and get things in order. Less interest in social media and things that I did because they gave me a small dopamin spike .
I think I'm doing more things that make long term sense .
I also feel a sense of appreciation and sometimes even happiness that is totally different from the feeling that dopaminergic drugs give you . It's only day 3 so take it with a grain of salt .

Plus the first 2 days I had diarrhea . So it's definitely doing something down there , I have chronic gut problems, so I'm sure it's detoxing something.
This mix is also prescribed for gut problems so it is normal to some degree .

That’s amazing, thanks buddy.

I was recommended this 2 years ago by a TCM Doctor and I totally forgot about it ???

 

[Mauritio]

That’s amazing, thanks buddy.

I was recommended this 2 years ago by a TCM Doctor and I totally forgot about it ???

Haha nice ? are you going to try it out ?

 

[Ismail]

Haha nice ? are you going to try it out ?

Definitely buddy, picking it up tomorrow hopefully ?

Will let you know how I get on etc. ?

 

[Ismail]

@Mauritio - I got the supplement (and another one recommended to use in tandem) yesterday. Started last night, will let you know how I get on. I had a strange dream, not sure if that's related, but hey lets see lol!

How you feeling?