Ray Peat Interview August 2020 - One Radio Network

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This is one of the best.

preferred to early about exosomes:

http://www.basic.northwestern.edu/g-buehler/FRAME.HTM

Nobody in his right mind would believe that the contractile protein molecules in a person's throat speak English. Clearly, the molecules follow orders issued ultimately by the person's brain. This is not a matter of the size of the organism. The contractile proteins in the muscle cells of a small nematode are not gliding or swimming, either. They, too, receive orders from the nervous system of the worm. In short, the interactions between the molecules of any organism generally do not create the functions of the organism, but it is the other way around: The functions of the organism initiate and control the interactions between its molecules. The necessity for such control is obvious. Using the example of contractile proteins, the molecules can only polymerize, depolymerize or slide along each other, but they would not know when and with what force and when to stop. A signal-integrating mechanism is required.
Why should the situation be different for single cells? After all protozoa are in effect small, but quite universal organism and the above conclusion should apply to them as much as to a fly, a frog or the author of this website. Yet, the vast majority of today's biologists devote their efforts to prove the opposite, namely that specific molecular interactions create the cellular functions such as cell division, directed locomotion, differentiation, design of the extracellular matrix, adhesion to materials and other cells and so forth.
My research for the past 30 years or so was devoted to examine whether cells have such signal integration and control center(s). The results suggest that mammalian cells, indeed, posess intelligence. The experimental basis for this conclusion is presented in the following web pages.
The most significant experimental results are:
1. The motile machinery of cells contains subdomains ('microplasts') that can be isolated from the cell and then are capable of autonomous movements. Yet, inside the cell they do not exercise their ability. The situation is comparable to a person's muscles that are capable of contraction outside a person's body, but do not contract at will once they are part of the person, suggesting that they are subject to a control center.
2. The cell as a whole is capable of immensely complex migration patterns for which their genome cannot contain a detailed program as they are responses to unforseeable encounters ( Cell movement is not random.. ).
3. Cells can 'see', i.e. they can map the directions of near-infrared light sources in their environment and direct their movements toward them. No such 'vision' is possible without a very sophisticated signal processing system ('cell brain') that is linked to the movement control of the cell. (The larger their light scattering, the larger the distance from which aggregating cells came together. )In addition there is the supporting theoretical consideration that the hiterto completely unexplained complex structure of centrioles is predicted in every detail if one asks what structure a cellular 'eye' should have. ( The structure of a pair of centrioles suggests their function as cellular eyes.)
 

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