Suikerbuik
Member
- Joined
- Jan 25, 2014
- Messages
- 700
I'd say it is modulating the immune system. 1,25D, via vitamin D receptor, upregulates parts of the innate immune system, down regulating parts of adaptive immunity, altering cytokine expression and else. The part that is being upregulated (by 1,25D) is involved in the antimicrobial host defense, reducing infection.
So you would indeed say let's use vitamin D, but in reality it is way more complex and actually supplemental vitamin D3 is tends to be counterproductive. Also if the Vit. D metabolism cannot regulate itself anymore, which is seen in many disease states. The increased 1,25D may have the ability to bind to other proteins like glucocorticoid receptor and thyroid receptors.
coincidentally I wrote my own exprience yesterday in another thread:
I start avoiding vitamin D supplements and things began to go better and better. A controversial thing is that when I initially started vitamin D suppletion I began feeling better in just a few weeks and felt really awesome 2 months after I began supplementing vitamin D. I even thought I was curing and advising vitamin D to a few relatives..... (at the time vitamin D was really hot topic - 2009/2010)
At this moment I am still avoiding vitamin D supplements, fatty fish and all that (i.e. cod liver oil).
Flu by the way doesn't have to say that much. Flu is the a result of certain cytokines, increasing metabolism by acting on the hypothmalus. Having flu every once in a while is actually a very good sign (not too often, once a year or every 2 years).
So you would indeed say let's use vitamin D, but in reality it is way more complex and actually supplemental vitamin D3 is tends to be counterproductive. Also if the Vit. D metabolism cannot regulate itself anymore, which is seen in many disease states. The increased 1,25D may have the ability to bind to other proteins like glucocorticoid receptor and thyroid receptors.
coincidentally I wrote my own exprience yesterday in another thread:
I start avoiding vitamin D supplements and things began to go better and better. A controversial thing is that when I initially started vitamin D suppletion I began feeling better in just a few weeks and felt really awesome 2 months after I began supplementing vitamin D. I even thought I was curing and advising vitamin D to a few relatives..... (at the time vitamin D was really hot topic - 2009/2010)
At this moment I am still avoiding vitamin D supplements, fatty fish and all that (i.e. cod liver oil).
Flu by the way doesn't have to say that much. Flu is the a result of certain cytokines, increasing metabolism by acting on the hypothmalus. Having flu every once in a while is actually a very good sign (not too often, once a year or every 2 years).