Aspirin Gave Me Permanent Tinnitus, Help

Discussion in 'Ask For Help or Advice' started by Astolfo, Sep 20, 2020.

Tags:
  1. Andman

    Andman Member

    Joined:
    Aug 1, 2017
    Messages:
    480
    well known side effect, glycine supplementation doesnt seem to do anything unfortunately
     
  2. Goat-e

    Goat-e Member

    Joined:
    Nov 14, 2013
    Messages:
    93
    Gender:
    Male
    I know. It's a pretty disturbing trend.
     
  3. Orion

    Orion Member

    Joined:
    Oct 23, 2015
    Messages:
    810
    @Astolfo Same aspirin gave me persistent tinnitus as well, from dosing experimentation about 3 years ago. Tried all the usual tips and suggestions, seems permanent at this point.
     
  4. postman

    postman Member

    Joined:
    Mar 3, 2016
    Messages:
    1,247
    Because it's on Ray's list of "safe supplements", accompanied with other stars such as retinol.
     
  5. Diokine

    Diokine Member

    Joined:
    Mar 2, 2016
    Messages:
    507
    Chronic ingestion of aspirin will inhibit COX2, leading to accumulation of arachidonic acid and reduction of peroxidised fatty acid molecules like prostaglandins, prostacyclins, and eicosanoids. This can shift the balance of NMDA activity. This shift can generate excessive electrical potential and induce currents in delicate structures like the auditory nerves and hair cells, this is interpreted as ringing. This excessive current can lead to damage, though it appears to be reversible in most cases. This is especially evident if phospholipase activity has been increased from adaptation to chronic inflammation, leading to higher levels of arachidonic acid.

    I think antagonizing NMDA activity can help to restore proper balance, and there are some relatively safe natural NMDA antagonists that may be helpful. These include limonene, valerian, and possibly lithium in proper dosing. Memantine and similar dimandoids may also be helpful. Sufficient magnesium intake will also be very important.

    Salicylate Enables Cochlear Arachidonic-Acid-Sensitive NMDA Receptor Responses

    Long‑term treatment with salicylate enables NMDA receptors and impairs AMPA receptors in C57BL/6J mice inner hair cell ribbon synapse

     
  6. Bogdar

    Bogdar Member

    Joined:
    Sep 5, 2018
    Messages:
    171
    Gender:
    Male
    That's not true; tinnitus has multiple causes, depending on them damage can be reversible. Idk how to help trauma dmg but I sure know how to improve my tinnitus (6 years old) and maybe treat it totally someday. I do also think that my tinnitus cause isn't that rare in tinnitus patient but juste missunderstood
     
  7. OP
    Astolfo

    Astolfo Member

    Joined:
    Aug 12, 2018
    Messages:
    553
    Gender:
    Male
    I have some at home. I will try but why did you recommend niacin? What it has to do with tinnitus?

    It's been same since i stopped taking it. I don't know why either.

    I'm pssd patient but it has nothing to do with tinnitus. It exactly started while im taking the aspirin and now it's permanent.

    Dude, what are you talking about? Get out of my thread.

    I have the same tinnitus for weeks. It is permanent.

    @Orion You ever tried NMDA antagonists?

    @Diokine Thanks for the study. I guess I was more vulnerable to such a damage as I have PSSD and lots of other metabolic problems. I'm probably in a chronic inflammatory state.
     
  8. Orion

    Orion Member

    Joined:
    Oct 23, 2015
    Messages:
    810
    I am quite wary of supplements now, so have not used those, but have tested niacin, lithium and magnesium dosing, no change.
     
  9. JKX

    JKX Member

    Joined:
    Apr 18, 2018
    Messages:
    253
    Gender:
    Male
  10. GenericName86

    GenericName86 Member

    Joined:
    Jun 30, 2018
    Messages:
    147
    Gender:
    Male
    Yep, supplementing gelatin and taurine (though im 99% sure it was the gelatin) corrected the tinnitus i got from going on aspirin benders.
     
  11. mrchibbs

    mrchibbs Member

    Joined:
    Nov 22, 2017
    Messages:
    1,808
    @Astolfo

    With all due respects, it is not permanent.

    If it was permanent, by definition why are you asking for help in resolving this issue?

    If it's permanent nothing can be done about it, it's for the rest of your life.

    This topic has been covered before and I have experienced tinnitus myself from large doses of aspirin.

    Aspirin needs to be dissolved in baking soda, taken with a meal with ample glycine.

    I myself dissolve some powder in hot water and baking soda, then I add a tablespoon of gelatin powder, stir well, wait till it stops foaming, then add some juice to fill the rest of the glass.

    Recommended reading:

    Negative effects of aspirin may be due to glycine depletion

    Do Your Aspirin Drills
     
  12. commas

    commas Member

    Joined:
    Jun 13, 2019
    Messages:
    754
    Gender:
    Male
    Hows your digestion?
     
  13. outcast1979

    outcast1979 Member

    Joined:
    Aug 20, 2020
    Messages:
    87
    Gender:
    Male
    Try B3,i am on b3 acetyl carnitine niacin and tribulus ,my tinnitus is over,i also suffer pssd,i was used a srni and a benzo in the past,and when i drop the drugs the tinnitus started.
     
  14. outcast1979

    outcast1979 Member

    Joined:
    Aug 20, 2020
    Messages:
    87
    Gender:
    Male
    For me the problem is anhedonia.
     
  15. pro marker

    pro marker Member

    Joined:
    Feb 26, 2020
    Messages:
    29
    Gender:
    Male
    how do you get so caught up in a diet that you tell someone theyre trolling when they are just sharing their experience? op tinnitus can be cured, there are many people who have regained silence after noise induced tinnitus even. my noise induced tinnitus has become much more quiet after a year. ***t sucks, and this is the reason ive never tried a drug. the less you stress out about the sound the quicker it will lessen.
     
  16. PhilParma

    PhilParma Member

    Joined:
    Sep 27, 2015
    Messages:
    352
    Gender:
    Male
    Location:
    Minnesota
    I currently have tinnitus. For many months I had been taking 100mg daily aspirin dissolved in baking soda and warm water. I've also taken 40-50g of gelatin daily, for years. I'm quitting aspirin and sticking with Vit E as needed.
     
  17. Lewis Acid

    Lewis Acid Member

    Joined:
    Mar 26, 2019
    Messages:
    261
    00:38

    Vitamin K
    Charcoal
    Taurine

    01:23

    Reduce Serotonin

    Also - 00:21

    Thyroid / Vitamin A / Progesterone

    Re-focusing on other things can create a natural biofeedback where you do not hear the sounds.
     
  18. Tash

    Tash New Member

    Joined:
    Dec 14, 2019
    Messages:
    4
    Gender:
    Female
    Amazing, thank you for your direction.

    This should be talked about more, I now get it temporarily after aspirin, plus my mother has had torturous tinnitus for years and I'd love to help her. Her colleagues mock her for not always hearing them and it breaks my heart.
     
  19. Kassy831

    Kassy831 New Member

    Joined:
    Sep 19, 2019
    Messages:
    2
    Gender:
    Female
    Just eat your daily carrot salad and mushrooms. Jp I know it's unfortunate but try not to stress and let it blend into your lifestyle till it's not noticeable and you can live free of stress. I have to live seeing Floaters in my eye, creepy at times but I've learned to accept and live stress-free, try to move on till it goes away by method of healing or by you not making it a part of your life. Sorry if not helpful wish you the best.
     
  20. GreenTrails

    GreenTrails Member

    Joined:
    Jul 31, 2020
    Messages:
    60
    Gender:
    Female
    When I was using large doses of aspirin, such as recommended by Ray Peat (6 gr per day, for cancer, which I have), and by Georgi Dinkov (18 325 gr. per day, for cancer), I was hearing noises in my head, which I would assume were tinninitis. It was terrible, and very annoying. I quit using aspirin in such heavy doses and the sounds went away. I now use 81 mg. per day, per my doctor's orders. Astolfo is not trolling. This is a real problem, at least it was for me. GreenDemiGod, when someone reports a problem that doesn't fit with your ideas, please don't call it trolling. That is what cults do.
     
Loading...