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Aspirin Decreases Cortisol And Increases Testosterone In Humans

Discussion in 'Scientific Studies' started by haidut, Mar 2, 2016.

  1. JackHanma

    JackHanma Member

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    Aren't most who are low thyroid high in potassium and low in sodium? Wouldn't this benefit low thyroid?
    Most people here experience great benefits from high sodium, which antagonizes potassium.
    Otherwise orange juice is highly consumed by most here for ample potassium.

    What is the mechanism that low potassium causes low zinc?

    Your premise is interesting though; many foods are high sources of salicylic acid, coconut oil being one, which is highly consumed amongst Peaters. I have never experimented with aspirin yet, but I wonder if my high coconut oil consumption increases the need for potassium and zinc.

    Nevertheless if your premises are true, couldn't one just increase potassium/zinc with aspirin as well as the noted vitamin k as other threads prescribe to counter any negatives?
     
  2. High_Prob

    High_Prob Member

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    If aspirin forcing potassium out of the cell is indeed a real concern then maybe taking some taurine with aspirin could possibly help (since it apparently helps to keep potassium and magnesium inside the cell).
     
  3. DaveFoster

    DaveFoster Member

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    @Serotoninja

    Aspirin tends to shift the cortisol and testosterone in favor of the latter.

    Correcting thyroid function tends to alleviate chronic inflammation without the need for aspirin.
     
  4. Frankdee20

    Frankdee20 Member

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    Oh ***t, for ever ? As in permanent?
     
  5. Diokine

    Diokine Member

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    I would say it is possible to induce a persistent cellular respiratory defect with chronic use of aspirin, but only in conditions of other feedback disruptions. Aldosterone and the renin-angiotensin system, along with cyclic AMP are critically involved in this feedback. Under a lot of stress, aldosterone will typically be chronically elevated. This chronic elevation of mineralcorticoid activity is what will eventually induce the persistent alkalosis.

    I wouldn't think it's appropriate to be afraid of aspirin causing permanent effects - though it can contribute to worsening pathology.
     
  6. Maggiemccall

    Maggiemccall Member

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    Does anyone know where one can get asprin without the talc in it? tis is in the UK.... but I do not mind getting it from abroad!
     
  7. lollipop

    lollipop Guest

    Amazon has a few options. GeriCare and another one I read about on this forum. The GeriCare off US Amazon has like 1000 tabs for $10 US dollars. Also someone from UK or EU might help you better as I am in US.

    Edit: Just saw that Health Natura sells Aspirin powder. I would feel confident with that product. You might check out their website. Many on the forum from all over the world order from him. I have as well.
     
  8. Wagner83

    Wagner83 Member

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  9. Benyamin Bulluc

    Benyamin Bulluc Member

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    The math of 5mg of aspirin to 100gms of body weight for a 65kg/143lbs person it is 325mg of aspirin.
     
  10. vulture

    vulture Member

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    Haidut's study seems contradicts the one I posted. But the one I posted doesn't show numbers. It might reduce T in 1%...also, Gbolduev said T reduction is permanent: wouldn't this mean anyone taking Aspirin for longer than a week should be presenting low T?
     
  11. Wagner83

    Wagner83 Member

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    I'd say it doesn't contradict the one you found, I could be wrong but as I read both abstracts, both showed higher T short term and when the one quoted by haidut ended (10 days I think) the other found decreased T (> 8-15 days ?).
     
  12. vulture

    vulture Member

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    As far as I remember at day 8 T dropped. Haidut's study might show increase but just because it wasn't enough time to see it decreased enough

    http://www.iosrjournals.org/iosr-jpbs/papers/Vol4-issue6/L0464954.pdf
    In this study dosage seems rather high, isn't it?
    Now, how could we reverse this effect? Has anyone seen this happen?

    I think it should be reversible or we would see a lot of aspirin users (who are also millions) with permanent low T
     
  13. Maggiemccall

    Maggiemccall Member

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    thank you Lisa!
     
  14. Wagner83

    Wagner83 Member

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    The study was done on rats, if I understand the content of this link properly and supposing it's accurate, then the equivalent for humans would be:
    (rat dose) / 6 = (human dose)
    10 / 6 = 1.6 mg/kg
    For a 70 kg male that would be 112mg of aspirin per day.
     
  15. vulture

    vulture Member

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    I have taken 325 mg for more than a week. And several members of this forum also
     
  16. Frankdee20

    Frankdee20 Member

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    How come if you google Aspirin and Testosterone” we get a lot of hits saying Aspirin lowers it
     
  17. Wagner83

    Wagner83 Member

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    Did you read the thread entirely? There might be some clues.
     
  18. Frankdee20

    Frankdee20 Member

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    Lol
     
  19. General Orange

    General Orange Member

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    Well, I have been taking 2x 160mg aspirin daily for 3 month now. It is working great in combination with training.

    first 1x 160mg + coffee milk sugar + calisthenics 10 minute workout, followed by breakfast: rice and chicken with gelatine, OJ, milk ginger sugar
    When doing heavy work in the yard I take up to 650mg beforehand to reduce aldosterone.
    and 1x 160mg at dinner. Sometimes 160mg before sleep or headaches.
     
  20. General Orange

    General Orange Member

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    Forgot to mention I eat pressure cooked red kidney beans that are high in potassium. And of course enough salt on the rice.
    This way, I think, with milk/calcium, beans/potassium, salt/sodium you will keep PH in balance even when you take Aspirin daily.

     
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