Aspirin Activates AMPK ,reduces Liver Fat

Mauritio

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Aspirin: New evidence is helping explain additional health benefits and open potential for new uses

This Studie found aspirin activates AMPK ,which is called the master regulator of metabolism . It is involved in mitochondrial biogenesis, weight loss etc...
They also found that aspirin reduces fatty liver and possibly diabetes type 2 ,which would make sense since AMPK activation is known to increase insulin sensitivity.

"We show that salicylate increases fat burning and reduces liver fat in obese mice and that this does not occur in genetically modified mice lacking the beta1 subunit of AMPK"

These findings are important as a large clinical trial is currently underway testing whether salsalate (a well-tolerated aspirin derivative), can prevent Type 2 diabetes.


 
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